ISSN: 2169-0138

Drug Designing: Open Access
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers
Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other
Subscription Journals (Source: Google Analytics)
Gjumrakch Aliev
Gjumrakch Aliev Gjumrakch Aliev
Professor of Cardiovascular, Neuropathology and Gerontology
University of Atlanta

Dr. Alliev is born on September 01, 1958 and is citizen of USA. He is currently President and CEO "GALLY” International Biomedical Research Consulting LLC. He is also Editor in Chief of other Journals like Open Journal Psychiatry, World Journal of Neuroscience, Applied Cell Biology. He also serves as an Chairman of Internationl Division of EuroEspes Biomedical Research Center on Spain and Vice chairman of EuroEspes Chair of Biotechnology & Genomics in Spain. He is also Professor of Cardiovascular, Neuropathology, Gerontology, Health Science and Healthcare Administration, Associate Director- Doctor of Science Program in Health Science and Healthcare Administration and Member of International Advisory Council/Board, University of Atlanta Monograph Series. He is Fluent in English, Russian, Azeri, Spanish, Italian and French. He completed his PhD in Cardiovascular Biology and Pathology, Neuroscience: Moscow State University, Moscow, Russia.

Research Interest

The present research interest includes Cell Biology, Biochemistry, and Functional Morphology of Cell and Tissues: Endothelial cells, Smooth Muscle Cells; Neurons and as well as Glial and Macrophages Cells.

Specific characteristic changes of cell biochemical properties and morphology in different functional states; particularly atherogenesis, vascular remodeling, hypertension, ischemia/reperfusion, tumor angiogenesis, signal transduction and mitochondria DNA deletion and/or overproliferation during cancer growth, metastases and Alzheimer’s diseases; 
Regulation biochemical mechanisms of specific nitric oxide synthase (NOS) expression in endothelial and smooth muscle cells and macrophages in vivo and in vitro; 
 At the present time, my lab is investigating the cellular and subcellular ultrastructural and molecular mechanisms of the features in the changes of mitochondria (DNA deletion, Cytochrome C Oxidase activity, redox activity (Fe), as well as protein modification and oxidation (HNE) and RNA (8HOG) oxidation during normal aging, atherosclerosis, tumor angiogenesis, stroke, human AD and transgenic mouse models of AD by using molecular biology and functional and structural methods (e.g., in situ hybridization and immunocytochemistry techniques at the light and electron microscopic levels). In addition, the biochemical properties of these protein activities will also be considered for our future studies. 
One of our newer research interests focuses on investigating the interaction of nanoparticles with tissues and cells. We have recently developed ways to determine the biological effects of nanoparticles in vivo and in vitro by utilizing animal models of human diseases. Our goal is to not only elucidate the pathogenic mechanisms underlying the nanoparticleseffects, but to also discover potential new drug development strategies. For example, our ongoing "In vitro Cancer Cell Line as a Model for the Peptide based new Drug Development" study has so far showed promising results regarding the specific delivery of drugs to tumor tissues. In another of our in vivo studies, we have found that nanoparticles are able to cross the blood brain barrier (BBB), which has been the biggest impediment in delivering drugs to patients with Alzheimers disease. We are using classical biochemistry, cell biology, and morphology techniques in conjunction with more modern methods, such as SEM/TEM SED X-ray elemental analysis and NMR studies of protein structure and dynamics, macromolecular interactions, mechanistic enzymology, and computational analyses and modeling, in order to determine the exact nature of the relationship between the nanoparticles and the underlying tissue.

Global Speakers in the subject

Global Experts in the subject


Phospholipase A2: A Potential Therapeutic Target in Inflammation and Cancer (In silico, In vitro, In vivo and Clinical Approach)

Nagendra sastry Yarla, Koduri Satyakumar, Duppalapudi Srinivasu, Kaladhar DSVGK, Gjumrakch Aliev, Gangappa Dharmapuri, Goutham Raju SP Swathi Putta, Srinivas Jagarlapoodi, Vemareddy Bheeram and Govinda Rao Duddukuri

Review Article: J Cancer Sci Ther/Vol.7.8 249-252 (2015)
doi: 10.4172/1948-5956.1000357
Mitochondria Specific Antioxidants and their Derivatives in the Context of the Drug Development for Neurodegeneration and Cancer

Gjumrakch Aliev, Hector H Palacios, Pablo Cacabelos and Ramon Cacabelos

Research Article: Drug Des 2012, 2: 103
doi: 10.4172/2169-0138.1000103

Drug Designing: Open Access - Oxidative Stress, Drug Development, Neurodegeneration and Cancer

Link Between Cancer and Alzheimer Disease via Oxidative Stress Induced by Nitric Oxide-Dependent Mitochondrial DNA Overproliferation and Deletion in the Context  of the Drug Development for Neurodegeneration and Cancer

Presented by: Gjumrakch Aliev
GALLY International Biomedical Research Consulting LLC

Download PPT PPT Views: 183 Updated on: 2015-09-18 For Recent Update: Click here
Download PDF   PDF Views: 183  Updated on: 2015-09-18 For Recent Update: Click here
OMICS International Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
OMICS International Conferences 2016-17
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

1-702-714-7001Extn: 9037

Business & Management Journals


1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

1-702-714-7001Extn: 9039

Materials Science Journals

Rachle Green

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

1-702-714-7001 Extn: 9042

© 2008-2016 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version