ISSN: 2329-6631

Journal of Developing Drugs
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Igor Astsaturov
Igor Astsaturov Igor Astsaturov
Department of Medical Oncology
Fox Chase Cancer Center

Igor Astsaturov, Assistant member from Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia. He has done Internship and Residency in Internal Medicine, Good Samaritan Hospital, Baltimore, MD and PhD in Hematology/Oncology, Russian Hematological Research Center, Moscow.

Research Interest

Intrinsic and acquired cellular resistance limits the efficacy of EGFR targeted cancer therapeutics. Rational and more efficacious combinations of targeted therapeutics, siRNA screening to comparatively probe the signaling network for proteins that regulate the effectiveness of both targeted (EGFR being the prime target) and chemotherapeutic agents, New synergistic targets with EGFR antagonists as a direct path to clinical exploitation of study results including distal sterol biosynthesis pathway metabolic enzymes such as SC4MOL and NSDHL using cellular systems and an animal model of conditional NSDHL deficiency. Explorations of new metabolic targets for cancer therapy involving these previously unexplored sterol pathway genes.


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Development of Cures in the Era of Genomic Medicine

Igor Astsaturov

Editorial: J Develop Drugs 2012, 1:e104
doi: 10.4172/2329-6631.1000e104
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