alexa
ISSN: 2329-6682

Gene Technology
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
Kameshwar P. Singh
Kameshwar P. Singh Kameshwar P. Singh
Department of Environmental Medicine
University of Rochester

Read Interview session with Kameshwar P. Singh
Biography

Dr. Singh received his degree in Veterinary Medicine from Ranchi College of Veterinary Science and Animal Husbandry, Ranchi, India in 1968-74. He also received specialized Master of Veterinary Science in Veterinary Bacteriology (including Virology, Mycology and Immunology) degree in 1974-76 from Indian Veterinary Research Institute (Ruhelkhand University), Bareilly, India. He began his carrier at the Industrial Toxicology Research Center (CSIR, Govt. of India), Lucknow, India (1977-1992), where became the head of Preventive Toxicology Division and Environmental Microbiology Division. He was selected Raman Research Fellow from CSIR and received postdoctoral training at Department of Surgical Oncology, UCLA Center for Health Sciences, University of California, Los Angeles in 1989. He subsequently moved to the Institute of Chemical Toxicology, Wayne State University, Detroit, MI, where served as Senior Research Associate and later worked as Research Scientist in Immunology and Microbiology Division, School of Medicine, Wayne State University (1993-2004). He moved to Environmental Medicine Division, School of Medicine and Dentistry, University of Rochester in 2004 and joined as Faculty. Dr. Singh has published more than 75 papers and two books. Currently, he is member of Editorial Board of several research journals including Stem Cell Biology and Research, and Veterinary World.

Research Interest

Aryl hydrocarbon receptor (AhR) belongs to the basic helix-loop helix family of DNA- binding proteins. AhR sense molecules and stimuli from cellular environment and initiate signaling cascades to elicit appropriate cellular responses. Though it binds to a diverse group of environmental chemicals, food and food products, the most potent AhR ligand known is 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). TCDD exposure produces a wide range of biological effects in animals. Increased incidences of leukemia and lymphoma have been reported in human populations exposed to TCDD and other related environmental chemicals. TCDD is classified as human carcinogen by IARC. Although AhR activation by TCDD has been known for its effects on the various physiological functions, studies on the role of AhR in hematopoietic stem cells functions are lacking. Hematopoietic stem cells (HSCs) are responsible for maintaining homeostasis of blood cells by differentiating to hematopoietic progenitor cells and ultimately to mature immune system lineage cells. They also self-renew to keep a constant pool of HSCs. Premitive HSCs are highly sensitive to environmental chemical insults that produce aberrant changes in differentiation and proliferation leading to development of hematopoietic diseases. Current research aims are as follows:
1. Does Aryl hydrocarbon receptor activation induce changes in hematopoietic stem cell functions?
2. Does Aryl hydrocarbon receptor deficiency produce alteration in primitive hematopoietic stem cells function?
3. Does Aryl hydrocarbon deficiency promote early aging and hematopoietic diseases?

Certificate
Certificate

Global Speakers in the subject

Global Experts in the subject

 
OMICS International Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
 
 
OMICS International Conferences 2016-17
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings
 
 

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

agrifoodaquavet@omicsonline.com

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

clinical_biochem@omicsonline.com

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

business@omicsonline.com

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

chemicaleng_chemistry@omicsonline.com

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

environmentalsci@omicsonline.com

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

engineering@omicsonline.com

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

generalsci_healthcare@omicsonline.com

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

genetics_molbio@omicsonline.com

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

immuno_microbio@omicsonline.com

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

omics@omicsonline.com

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

materialsci@omicsonline.com

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

mathematics_physics@omicsonline.com

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

medical@omicsonline.com

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

neuro_psychology@omicsonline.com

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

pharma@omicsonline.com

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

social_politicalsci@omicsonline.com

1-702-714-7001 Extn: 9042

 
© 2008-2016 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version