alexa Syphilis a Reversible Cause of Dementia | Open Access Journals
ISSN: 2167-7182
Journal of Gerontology & Geriatric Research
Make the best use of Scientific Research and information from our 700+ peer reviewed, Open Access Journals that operates with the help of 50,000+ Editorial Board Members and esteemed reviewers and 1000+ Scientific associations in Medical, Clinical, Pharmaceutical, Engineering, Technology and Management Fields.
Meet Inspiring Speakers and Experts at our 3000+ Global Conferenceseries Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on
Medical, Pharma, Engineering, Science, Technology and Business

Syphilis a Reversible Cause of Dementia

Ishrat Ansari* and George T. Grossberg
Division of Geriatric Psychiatry, St Louis University School of Medicine, Missouri, USA
Corresponding Author : Ishrat Ansari
Division of Geriatric Psychiatry
Department of Neurology & Psychiatry
St Louis University School of Medicine
Missouri, USA
Tel:
3149969689
E-mail: ishrata@gmail.com
Received: August 12, 2015 Accepted: August 25, 2015 Published: August 27, 2015
Citation: Ansari I and Grossberg GT(2015) Syphilis a Reversible Cause of Dementia. J Gerontol Geriatr Res S4:003. doi: 10.4172/2167-7182.S4-003
Copyright: © 2015 Ansari I, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Visit for more related articles at Journal of Gerontology & Geriatric Research

Keywords
Neurosyphilis; Mild to moderate neurocognitive impairment and reversible dementia
Introduction
This is a case of a patient who presented to our Geriatric Psychiatry Division with Major Depressive Disorder, severe, recurrent with psychotic features and mild cognitive impairment with bilateral lower extremity pain. Patient was diagnosed with Neurosyphilis
Case Report
This article describes a case of a 71-year-old patient of Ethiopian background who presented to the Geriatric Psychiatry inpatient unit for worsening of depression and memory problems with progressive cognitive decline and behavioral changes over the last several years. The patient also had persecutory delusions and was unable to perform ADL’s and IADL’s. The patient had previous multiple psychiatric hospitalizations for major depressive disorder, severe, recurrent with psychotic features and was treated with antidepressants and antipsychotics without any significant improvement in symptoms. Patient also reported bilateral lower extremity pain. We performed a complete clinical and laboratory work up for reversible cause of dementia. CSF analysis showed raised protein and cell count. The diagnosis of Neurosyphilis was established based on positive serum RPR and FTA-ABS tests along with neurological and behavioral sign and symptoms. Patient was treated with high dose penicillin for 10 days. At one year follow up improvement was noted clinically and the patient was able to perform her ADL’s and IADL’s along with improvement of depression and psychotic features.
Conclusion
Often there are times when “reversible dementias” do not present with cognitive or behavioral symptoms that are severe enough to meet the criteria of major or mild cognitive impairment. It is prudent to diagnose and treat mild cognitive impairment with reversible etiology in psychiatric settings. This case stresses the import of performing the screening test for reversible causes of dementia including RPR, especially in patients with a background where syphilis is prevalent along with cognitive impairment with neurological signs. While the etiologies of reversible dementia may be treatable, and improves the patient’s overall functioning, full reversal of symptoms of dementia should not be assumed.
Select your language of interest to view the total content in your interested language
Post your comment

Share This Article

Relevant Topics

Recommended Conferences

Article Usage

  • Total views: 11627
  • [From(publication date):
    specialissue-2015 - Jul 27, 2017]
  • Breakdown by view type
  • HTML page views : 7858
  • PDF downloads :3769
 
 

Post your comment

captcha   Reload  Can't read the image? click here to refresh

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

agrifoodaquavet@omicsonline.com

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

clinical_biochem@omicsonline.com

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

business@omicsonline.com

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

chemicaleng_chemistry@omicsonline.com

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

environmentalsci@omicsonline.com

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

engineering@omicsonline.com

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

generalsci_healthcare@omicsonline.com

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

genetics_molbio@omicsonline.com

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

immuno_microbio@omicsonline.com

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

omics@omicsonline.com

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

materialsci@omicsonline.com

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

mathematics_physics@omicsonline.com

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

medical@omicsonline.com

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

neuro_psychology@omicsonline.com

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

pharma@omicsonline.com

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

social_politicalsci@omicsonline.com

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version