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ISSN: 2169-0111

Advancements in Genetic Engineering

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Diego Alexander Garzo-Alvarado
Universidad Nacional de Colombia

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Ming Pei
West Virginia University

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Arvind Chhabra
University of Connecticut Health Center

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About the Journal

Impact Factor: 1.00 *

NLM ID:101600827
ISSN: 2169-0111

Genetic Engineering is a technique of controlled manipulation of genes to change the genetic makeup of cells and move genes across species boundaries to produce novel organisms. Advancements in Genetic Engineering journal provide an opportunity to share the information on Genetic engineering techniques and its application to numerous fields of research, biotechnology, and medicine among scientists and researchers.

The journal includes a wide range of fields in its discipline to create a platform for the authors to make their contribution towards the journal and the editorial office promises a peer review process for the submitted manuscripts for the quality of publishing. Advancements in Genetic Engineering focused on the areas such as Mutant organisms, DNA Replication, Recombinant DNA, Genetic linkage analysis, Genetically Modified Plants, Genetically Modified Animals, DNA Microarray, Green Fluorescent Protein, Protein Sequencing, Genetic Probes, RNA Splicing, Functional Genomics, Antisense RNA, RFLP, Biosafety of GMO, GMO Ethics , Genetically Engineered Microorganism, Computational genomics Advancements in Genetic Engineering is an Open Access journal and aims to publish most complete and reliable source of information on the discoveries and current developments in the mode of original articles, review articles, case reports, short communications, etc. in all areas of the field and making them freely available through online without any restrictions or any other subscriptions to researchers worldwide.

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Human genetic engineering

Human Genetic engineering is the deliberate, controlled manipulation of the genes in an organism with the intent of making that organism better in some way. This is usually done independently of the natural reproductive process.

Gene editing is a recently developed type of genetic engineering in which DNA is inserted, replaced, or removed. Here, experts weigh-in with ethical questions and considerations. Chinese scientists say they've genetically modified human embryos for the very first time.

Related journals of Human genetic engineering

Cell & Developmental Biology , Advancements in Genetic Engineering, Stem Cell Research & Therapy, American Journal of Human Genetics,  Annals of Human Genetics,  Annual Review of Genomics and Human Genetics, Current Protocols in Human Genetics,  Egyptian Journal of Medical Human Genetics, European Journal of Human Genetics, Human Genetics, Indian Journal of Human Genetics, International Journal of Human Genetics, Journal of Human Genetics, Monographs in human genetics, Twin Research and Human Genetics.

Genetically engineering foods

Genetic engineering modifies the DNA of crops to display specific traits, such as a resistance to pesticides and herbicides. Genetically engineered (GE) crops are often also referred to as genetically modified organisms (GMOs) or biotech crops. In recent years, the Food and Drug Administration began paving the way for approval of GM animals, such as salmon. The first genetically modified animal approved for human consumption, supporters of GM salmon claim it grows at twice the normal rate.

Related journals of Genetically engineering foods

Clinical & Medical Genomics, Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology, Cereal Foods World, Healthcare foodservice, Journal of Functional Foods, Journal of Muscle Foods, Journal of Foodservice Business Research, Plant Foods for Human Nutrition, Quality Assurance and Safety of Crops and Foods.

Genetically engineered animals

A genetically engineered organism, also known as a transgenic organism, is any organism whose genetic material has been altered using genetic engineering techniques. GEOs are the source of genetically modified foods and are also widely used in scientific research and to produce goods other than food. The term GEO is very close to the technical legal term, 'living modified organism', defined in the Cartagena Protocol on Biosafety, which regulates international trade in living GEOs (specifically, "any living organism that possesses a novel combination of genetic material obtained through the use of modern biotechnology").

Related journals of Genetically engineered animals

Fungal Genomics & Biology, Gene Technology, Genetic Disorders & Genetic Reports Hybrid, Genetic Syndromes & Gene Therapy. Hereditary Genetics: Current Research, ATLA Alternatives to Laboratory Animals, Biology of Growing Animals, Experimental Animals, Genome Mapping and Genomics in Animals, Journal of Venomous Animals and Toxins, Journal of Venomous Animals and Toxins Including Tropical Diseases, Laboratory Animals, Reproduction in Domestic Animals, Society and Animals.

Genetic Probes

Genetic Probes is a fragment of DNA or RNA of variable length (usually 100-1000 bases long) which is radioactively labelled used in DNA or RNA samples to detect the presence of nucleotide sequences (the DNA target) that are complementary to the sequence in the probe. The probe thereby hybridizes to single-stranded nucleic acid (DNA or RNA) whose base sequence allows probe-target base pairing due to complementarity between the probe and target.

 Related journals of Genetic Probes

Molecular and Genetic Medicine, Molecular Biology, Molecular Biomarkers & Diagnosis, Recombination Hybrid European Journal of Medical Genetics, Forensic Science International: Genetics, Genes and Genetic Systems, Genetic Resources and Crop Evolution, Genetic Testing and Molecular Biomarkers, International Journal of Immunogenetics,  Journal of Animal Breeding and Genetics.

Gene cloning

Gene cloning is the process in which a gene of interest is located and copied (cloned) out of DNA extracted from an organism? When DNA is extracted from an organism, all of its genes are extracted at one time. This DNA, which contains thousands of different genes.

The step following DNA extraction of an organism is the construction of a library to organize the DNA. A gene library can be defined as a collection of living bacteria colonies that have been transformed with different pieces of DNA from the organism that is the source of the gene of interest. If a library is to have a colony of bacteria for every gene, it will consist of tens of thousands of colonies or clones.

 Related journals of Gene cloning

Advances in Genetic Engineering & Biotechnology Hybrid, Advances in Molecular Diagnostics, Biotechnology & Biomaterials, Gene Expression Patterns, General Relativity and Gravitation,  Genes and Genetic Systems, Genes, Brain and Behavior,  Genetic Resources and Crop Evolution, Genetica, Genetical Research, Genetics Selection Evolution.


RFLP (often pronounced "rif lip", as if it were a word) is a method used by molecular biologists to follow a particular sequence of DNA as it is passed on to other cells. RFLPs can be used in many different settings to accomplish different objectives.

Each organism inherits its DNA from its parents. Since DNA is replicated with each generation, any given sequence can be passed on to the next generation. An RFLP is a sequence of DNA that has a restriction site on each end with a "target" sequence in between. A target sequence is any segment of DNA that bind to a probe by forming complementary base pairs. A probe is a sequence of single-stranded DNA that has been tagged with radioactivity or an enzyme so that the probe can be detected. When a probe base pairs to its target, the investigator can detect this binding and know where the target sequence is since the probe is detectable. RFLP produces a series of bands when a Southern blot is performed with a particular combination of restriction enzyme and probe sequence.

 Related journals of RFLP

Gene Technology, Genetic Disorders & Genetic Reports Hybrid, Genetic Syndromes & Gene Therapy, Hereditary Genetics: Current Research, Epigenetics and Human Health, European journal of genetics in society : an ethical approach to genetics, Genetics and Breeding, Genetics and EpiGenetics,  Human Ontogenetics, Immunology and Immunogenetics Insights.


Transgenes is the process of introducing an exogenous gene — called a transgene — into a living organism so that the organism will exhibit a new property and transmit that property to its offspring. Transgenes can be facilitated by liposomes, plasmid vectors, viral vectors, pronuclear injection, protoplast fusion, and ballistic DNA injection. Transgenesis is the process of introducing an exogenous gene — called a transgene — into a living organism so that the organism will exhibit a new property and transmit that property to its offspring.

Related journals of Trans-Genesis

Advances in Molecular Diagnostics, Biotechnology & Biomaterials, Cell Biology: Research & Therapy Hybrid, Angiogenesis, Carcinogenesis  Environmental and Molecular Mutagenesis, Genesis,  Molecular Carcinogenesis, Mutagenesis.

Insulin genetics

The Insulin genetics provides instructions for producing the hormone insulin, which is necessary for the control of glucose levels in the blood. Glucose is a simple sugar and the primary energy source for most cells in the body.
Insulin is produced in a precursor form called proinsulin, which consists of a single chain of protein building blocks (amino acids). The proinsulin chain is cut (cleaved) to form individual pieces called the A and B chains, which are joined together by connections called disulfide bonds to form insulin.

 Related journals of Insulin genetics

Gene Technology, Genetic Disorders & Genetic Reports Hybrid, Genetic Syndromes & Gene Therapy, Hereditary Genetics: Current Research, Human Genetics & Embryology, Advances in Genetics, BMC Medical Genetics,  BMC Genetics, Conservation Genetics,  Epigenetics, Infection, Genetics and Evolution, Journal of Assisted Reproduction and Genetics, Neurogenetics, Psychiatric Genetics.

DNA Replication

DNA replication is the process of producing two identical replicas from one original DNA molecule. This biological process occurs in all living organisms and is the basis for biological inheritance.

DNA replication is the process by which DNA makes a copy of itself during cell division.

The first step in DNA replication is to ‘unzip’ the double helix structure of the DNA? molecule.
This is carried out by an enzyme? called helicase which breaks the hydrogen bonds? holding the complementary? bases? of DNA together (A with T, C with G).
The separation of the two single strands of DNA creates a ‘Y’ shape called a replication ‘fork’. The two separated strands will act as templates for making the new strands of DNA.
One of the strands is oriented in the 3’ to 5’ direction (towards the replication fork), this is the leading strand?. The other strand is oriented in the 5’ to 3’ direction (away from the replication fork), this is the lagging strand?.

 Related journals of DNA Replication

Single Cell Biology, Stem Cell Research & Therapy, Tissue Science & Engineering, DNA Repair, DNA Research, Mitochondrial DNA, Mobile DNA, Mutation Research - DNA Repair.

Genetic engineering application

Genetic engineering, also called genetic modification, is the direct manipulation of an organism's genome using biotechnology. New DNA may be inserted in the host genome by first isolating and copying the genetic material of interest using molecular cloning methods to generate a DNA sequence, or by synthesizing the DNA, and then inserting this construct into the host organism. Genes may be removed, or "knocked out", using a nuclease. Gene targeting is a different technique that uses homologous recombination to change an endogenous gene, and can be used to delete a gene, remove exons, add a gene, or introduce point mutations.

Related journals of Genetic engineering application

Human Genetics & Embryology, Insights in Stem Cells, Molecular and Genetic Medicine, Molecular Biology, Biotechnology and Genetic Engineering Reviews, Genetic engineering, Genetic Engineering and Biotechnology Journal,  Genetic Engineering and Biotechnology News.

Ethics in genetic engineering

Ethical issues, including concerns for animal welfare, can arise at all stages in the generation and life span of an individual genetically engineered animal. The following sections detail some of the issues that have arisen during the peer-driven guidelines development process and associated impact analysis consultations carried out by the CCAC. The CCAC works to an accepted ethic of animal use in science. However, despite the steps taken to minimize pain and distress, there is evidence of public concerns that go beyond the Three Rs and animal welfare regarding the creation and use of genetically engineered animals.

Related Journals of Ethics in genetic engineering

Current Synthetic and Systems Biology, Gene Technology, Genetic Disorders & Genetic Reports Hybrid, Advances in Genetics, BMC Medical Genetics, BMC Genetics, Conservation Genetics, Epigenetics, Infection, Genetics and Evolution, Journal of Assisted Reproduction and Genetics, Neurogenetics, Psychiatric Genetics.

Recombinant DNA

Recombinant DNA (rDNA) molecules are DNAmolecules formed by laboratory methods of genetic recombination (such as molecular cloning) to bring together genetic material from multiple sources, creating sequences that would not otherwise be found in biological organisms.

A series of procedures that are used to join together (recombine) DNA segments. A recombinant DNA molecule is constructed from segments of two or more different DNA molecules. Under certain conditions, a recombinant DNA molecule can enter a cell and replicate there, either on its own or after it has been integrated into a chromosome.

Related journals of Recombinant DNA

Down Syndrome & Chromosome Abnormalities, Fungal Genomics & Biology, Gene Technology, Genetic Disorders & Genetic Reports Hybrid, Genetic Syndromes & Gene Therapy, Advances in DNA Sequence-Specific Agents, Artificial DNA: PNA and XNA,  DNA Reporter.

RNA Splicing

In molecular biology and genetics, splicing is a modification of the nascent pre-messenger RNA (pre-mRNA) transcript in which introns are removed and exons are joined. For nuclear encoded genes, splicing takes place within the nucleus after or concurrently with transcription.

Related Journals of RNA Splicing

Gene Technology, Fungal Genomics & Biology, Advancements in Genetic Engineering, Advances in Genetics,  BMC Medical Genetics,  BMC Genetics,  Conservation Genetics,  Epigenetics  Infection, Genetics and Evolution, Journal of Assisted Reproduction and Genetics,  Neurogenetics, Psychiatric Genetics.

Green genetic engineering

Green genetic engineering as it is used in agriculture and the food industry is all about creating new species of plants that are highly resistant to pests and pesticides or contain higher levels of nutrients than traditional plants. The idea is not new; in fact, farmers have been doing this for thousands of years, crossing and breeding plants to produce new and stronger species.The application of genetic engineering to plant breeding (so-called “green genetic engineering”) has been the subject of controversial debate for many years. Which benefits and risks would be linked to the cultivation of genetically modified crops in Switzerland? How should research and cultivation be regulated? Which ethical questions have to be considered? The Forum for Genetic Research promotes fact-based dialogue based on science.

Related Journals of Green genetic engineering

Cell Science & Therapy, Cellular and Molecular Biology, Clinical & Medical Genomics, Cloning & Transgenesis, Biotechnology and Genetic Engineering Reviews, Genetic engineering, Genetic Engineering and Biotechnology Journal, Genetic Engineering and Biotechnology News.

Genetic engineering crops

Genetically engineering crops, biotech crops are plants used in agriculture, the DNA of which has been modified using genetic Engineering techniques In most cases the aim is to introduce a new trait to the plant which does not occur naturally in the species. Examples in food crops include resistance to certain pests, diseases, or environmental conditions, reduction of spoilage, or resistance to chemical treatments (e.g. resistance to a herbicide), or improving the nutrient profile of the crop. Examples in non-food crops include production of pharmaceutical agents, biofuels, and other industrially useful goods, as well as for bioremediation.

Related Journals of Genetic engineering crops

Cell Biology: Research & Therapy Hybrid, Cloning & Transgenesis, Current Synthetic and Systems Biology, Down Syndrome & Chromosome Abnormalities, Fungal Genomics & Biology, GM crops, GM crops & food, Industrial Crops and Products, Quality Assurance and Safety of Crops and Foods, Research on Crops, Turkish Journal of Field Crops, Vegetable Crops Research Bulletin, Field Crops Research.

Functional Genomics

Functional genomics is a field of molecular biology that attempts to make use of the vast wealth of data produced by genomic and transcriptomic projects (such as genome sequencing projects and RNA-seq) to describe gene (and protein) functions and interactions.

The aim of functional genomics studies is to understand the complex relationship between genotype and phenotype on a global (genome-wide) scale. Studies investigate a range of processes such as transcription, translation and epigenetic regulation.

Related Journals of Functional Genomics

Molecular Biomarkers & Diagnosis,Genetic Disorders & Genetic Reports, Nanomedicine & Biotherapeutic Discovery, Phylogenetics & Evolutionary Biology, Single Cell Biology, Briefings in Functional Genomics, Briefings in Functional Genomics and Proteomics, Comparative and Functional Genomics, Journal of Structural and Functional Genomics.

OMICS International Organises 1000+ Conferences Every Year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 700+ Open access journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Advancement in Genetic Engineering is associated with  “4th International conference on Clinical Microbiology & Microbial Genomics” (Clinical Microbiology-2015) during October 05-07, 2015 at Philadelphia, USA. with a theme "Analyzing The Innovation & Future Trends In Clinical Microbiology ". We are particularly interested in Genetics research in the areas of genomics, Mutant organisms, DNA Replication, Recombinant DNA, Genetic linkage analysis, Genetically Modified Plants, Genetically Modified Animals, DNA Microarray, Green Fluorescent Protein, Protein Sequencing, and Genetic Probes. We encourage articles involving genome-wide DNA methylation mapping and gene expression including histone replacement, messenger RNA interference (miRNA) as well any other epigenetic studies.



*Unofficial 2014 Impact Factor was established by dividing the number of articles published in 2012 and 2013 with the number of times they are cited in 2014 based on Google search and the Scholar Citation Index database. If 'X' is the total number of articles published in 2012 and 2013, and 'Y' is the number of times these articles were cited in indexed journals during 2014 than, impact factor = Y/X


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