The Journal, Drug Designing Open Access publishes the highest quality scientific articles amalgamating broad range of fields including molecular modeling, clinical research and drug discovery and delivery.
The journal focuses on all fields of drug design including drug discovery, drug design by rational approach, target-based design, drug synthesis, drug metabolism, structure-based drug design, molecular modeling, ligand-based interaction, development of the generic drug, in silico chemoinformatics and bioinformatics technologies, receptor agonist/antagonist, protease substrate/inhibitor, peptidomimetic, Quality by design, Design for reliability in drug development, Design for traditional Chinese medicine clinical trials, Bayesian sequential design for multi-regional design, Design and analysis for target clinical trials, Design and analysis for diagnostic procedures, Adaptive design for early clinical development, Design for biosimilar studies, Design for bioassay development and validation, Design for statistical genetics, Design for assessment of drug to drug interaction, Design for bridging studies, Design for stability analysis, etc.
This scientific journal includes a wide range of fields in its discipline to create a platform for the authors to make their contribution towards the journal and the editorial office at Omics International promises a peer review process for the submitted manuscripts to maintain the quality of free journals. The jounal is among the best open access journals and aims to publish most complete and reliable source of information on the discoveries and current developments in the mode of original articles, review articles, case reports, short communications, etc. in all areas of the field.
Article published in drug designing journal are freely available online without any restrictions or any other subscriptions to the researchers worldwide. The journal is using Editorial Tracking System for quality in peer review process.
Drug designing journals have been showing tremendous citations and articles focusing the most advanced research trends in the field of drug discovery, medicinal chemistry, Drug Design tools, protein engineering, bioinformatics.
Editorial Manager is an online manuscript submission, review and tracking systems. Review processing is performed by the editorial board members of Drug Designing: Open Access or outside experts; at least two independent reviewer’s approval followed by editor approval is required for acceptance of any citable manuscript. Authors may submit manuscripts and track their progress through the system, hopefully to publication. Reviewers can download manuscripts and submit their opinions to the editor. Editors can manage the whole submission/review/revise/publish process.
Drug design is an splendid inventive process of new medication on the basis of biological target. It is also known as rational drug design or rational design. That is the invention in medical history in order to yield significant therapeutic response. The drug is an organic molecule, when it is bind to target site it can either inhibit or activate the function of a biomolecule which results in therapeutic benefit. The drug design involves the design of such molecules that are similar to the bio molecular target site in shape and charge in order to bind to it. Drug design relies on the knowledge of the three dimensional structure of bimolecular targets.
Related Journals of Drug Designing
International Journal of Drug Development & Research, Pharmaceutics & Drug Delivery Research, Chemical Biology and Drug Design, Anti-Cancer Drug Design, Drug Design, Development and Therapy, Drug Design and Discovery, Current Computer-Aided Drug Design, Advances in Antiviral Drug Design, Drug Design Reviews Online, Frontiers in Drug Design and Discovery and International Journal of Computational Biology and Drug Design.
Fragment based drug design is identification of fragments or components of low molecular weight or lead compounds, which can bind with weak affinity to the target site. Fragment based discovery involved finding such weakly binding fragments and grow them or combine them in order to create lead components with higher affinity or selectivity to bimolecular target site. These techniques achieved credible success in drug development.
Related Journals of Fragment based Drug Designing
Molecular Enzymology and Drug Targets, Advances in Pharmacoepidemiology & Drug Safety, Advances in Antiviral Drug Design, Drug Design Reviews Online , Frontiers in Drug Design and Discovery and International Journal of Computational Biology and Drug Design and Chemical Biology & Drug Design.
Structure based drug design is the process of designing a chemical structure with the objective of identifying a compound which suits for clinical tests. The process involves how that shapes and charges to interact with biological target inorder to yield therapeutic activity. Structure based drug design based on three dimensional structures strictly.
Related Journals of Structure based Drug Designing
Developing Drugs, Pharmaceutical Sciences & Emerging Drugs, Biomolecular Research & Therapeutics, Assay and Drug Development Technologies, Recent Patents on CNS Drug Discovery, Drug Discovery Today: Technologies, Drug Development and Industrial Pharmacy, Recent Patents on Anti-Infective Drug Discovery, Current Drug Discovery Technologies, Drug Discovery Today: Disease Mechanisms, Recent Patents on Inflammation and Allergy Drug Discovery, Drug Discovery Today: Disease Models and Recent Patents on Cardiovascular Drug Discovery.
In silico methods with use of bioinformatics are in increasing demand in drug discovery and development that can identify and analyze active sites and suggest potential drug molecules that can bind to these sites specifically. They analyze the target structures for possible binding sites, generate candidate molecules, check for their drug likeness, dock these molecules with the target, rank them according to their binding affinities, further optimize the molecules to improve binding characteristics.
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Biodiscovery, Nanomedicine & Biotherapeutic Discovery, Nature Reviews Drug Discovery, Drug Discovery Today, Current Opinion in Drug Discovery and Development, Perspectives in Drug Discovery and Design, Expert Opinion on Drug Discovery, Drug Discovery Today: Technologies, Current Drug Discovery Technologies, Recent Patents on Anti-Cancer Drug Discovery, Recent Patents on CNS Drug Discovery.
Molecular modeling is a tool which helps in the generation, manipulation or representation of three dimensional structures of molecule and associated physico chemical properties as well. it involves use of computerized techniques based on theoretical chemistry methods and experimental data to predict molecular and biological properties. Molecular modeling helps to investigate, interpret and discovery of new phenomena.
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Molecular Imaging & Dynamics, Molecular Medicine & Therapeutics, Biomolecular Research & Therapeutics, Molecular Enzymology and Drug Targets, Molecular Pharmaceutics & Organic Process Research, Journal of Molecular Modeling, Journal of Molecular Graphics and Modelling, Journal of chemical information and modeling, Journal of Chemistry, Molecular Systems Biology, Molecular Biology & Evaluation , Molecular Aspects of Medicine.
Heat shock proteins are the proteins that produced when cells are expose to the biologically stressful conditions. Some selected heat shock proteins also known as chaperones. Increased temperature and some internal changes such as PH change will lead to the proteins to denature which cannot morphologically, functionally normal and leads to unfold of proteins that miss folded proteins aggregates and eventually kills the cell. Heat Shock Proteins are induced rapidly at high levels to deal with this problem. These can able to mediate the synthesis, stability and transulation ability of mRNA.
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Proteomics & Enzymology,Bioenergetics: Open Access, Biochemistry & Physiology: Open Access, Proteins Structure, Function and Genetics, Biochimica et Biophysica Acta - Proteins and Proteomics, Probiotics and Antimicrobial Proteins, Amino Acids, Peptides and Proteins, International Journal of Medical Science and Public Health, BioOne, The Journal of Biological Chemistry, Journal of Experimental Biology, Journal of National Cancer Institute.
Antigen – antibody reaction is a chemical interaction between antigens of cell surface and antibodies which are produced by the B-lymphocytes of the white blood cells. Each antibody can bound with specific antigen which is due to specific chemical constitution of the particular antibody. I it doesn’t happen so it leads to cross linking which is fatal . This is the reaction which keeps the body free from and protected from pathogens, chemical toxins and foreign bodies. Immunity of the humans is mediated by this specific phenomena.
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Nanomedicine is the application of the nanotechnology, which ranges from application of nanomaterials to nanoelectronic biosensors medicinally. The functionality can be attain to nanomedicine by interact with them biomolecule. As most of nanomaterial structure is similar to the biological structures these can be widely useful for in vitro and in vivo researches. With of invention its widely using in the development of diagnostic devices, analytical tools, drug delivery vehicles and physical therapy applications.
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In pharmacology the agonist- antagonist are the type of receptor ligand or drug which binds to the receptor and mediates the therapeutic response either by activates or blocks the receptor. Agonists activates receptors to produce desired action whereas the antagonists blocks the action of agonist upon the binding to receptor. inverse agonist causes to action against to that of agonist.
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Peptidomimetics are the compounds whose pharmacophores that is their essential elements mimic a natural peptide or protein in order to retain the ability to interact with the specified biological target and produce same biological effect. This can form either rom modification of the persistent peptide or by designing the peptoids and β-peptides. With the changed structure can attain significant molecular properties like desired biological activity and stability.
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Biotechnology & Biomaterials, Biochemistry & Molecular Biology, Journal Polymer Journal, Frontiers, PLOS One, Bentham Science, Journal of the American Chemical Society.
Proteases are the enzymes that are responsible for proteolysis that is cleave of proteins by hydrolysis of peptide bonds that links amino acids which are in peptide chain. These are responsible for many life and death processes. Whereas protease inhibitors are blocks the activity of protease enzymes which helps in the growth life threatening viruses and immature them and make them unable to infect new cells.
Related Journals of Protease Substrates/ Inhibitors
Proteomics & Enzymology, Enzyme Engineering, Molecular Enzymology and Drug Targets, Journal of Biological Chemistry, Journal of Medicinal Chemistry, Chemical Communications, Enzymes, Nature international weekly Journal of Science, Scientific Research Publishing.
Virtual screening is a computational method which plays a key role in drug discovery. it is used to search small molecule libraries to find the structures those which likely bind or interact with drug target. It is also defined as "automatically evaluating very large libraries of compounds" using computer programs. As the accuracy of this method is increased it is widely using in drug design process.
Related Journals of Screening and Drug Design
Nanomedicine & Biotherapeutic Discovery, Biodiscovery, Journal of Biomolecular Screening, Combinatorial Chemistry and High Throughput Screening, Journal of Medical Screening, Screening, ASSAY and Drug Development Technologies,International Journal of High Throughput Screening.
Nanotechnology includes the engineering of functional systems at the molecular scale which are characterized by unique physical, optical and electronic features that are attractive for disciplines ranging from materials science to biomedicine. The use of nanotechnology in drug development is the developing process where the nanoparticles used to deliver the drug to the particular cell which is diseased. By this technology the particles which are engineered in such a way that they can attract to the diseased cell and allows treatment to the particular cell directly. Through this unique technique can minimize the damage of healthy cells in the body.
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Nanomedicine & Biotherapeutic Discovery,Biodiscovery, Nano Research & Applications, Nanomaterials & Molecular Nanotechnology,Nanomedicine & Biotherapeutic Discovery, Journal of Nanomedicine and Nanotechnology, Journal of Nanotechnology, Nanomaterials and Nanotechnology, Nanotechnology Perceptions, International Journal of Green Nanotechnology: Physics and Chemistry, Nanoscience and Nanotechnology, International Journal of Green Nanotechnology: Materials Science and Engineering, RSC Nanoscience and Nanotechnology, International Journal of Green Nanotechnology.
*Unofficial 2015 Journal Impact Factor was established by dividing the number of articles published in 2013 and 2014 with the number of times they are cited in 2015 based on Google search and the Scholar Citation Index database. If 'X' is the total number of articles published in 2013 and 2014, and 'Y' is the number of times these articles were cited in indexed journals during 2015 then, impact factor = Y/X