ISSN: 2168-9652

Biochemistry & Physiology: Open Access

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Editorial Board

Masayoshi Yamaguchi

Editor-in-Chief
Masayoshi Yamaguchi
Department of Hematology and Medical Oncology
Emory University School of Medicine
Atlanta
USA

Biography :

Masayoshi Yamaguchi, Ph.D., IOM, FAOE, DDG, DG, is Adjunct Professor, Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA (2013-); Visiting Professor in Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Baylor College of Medicine, Houston, TX, USA (2012–2013); Visiting Professor in Department of Pathobiology, College of Veterinary Medicine, The University of Missouri-Columbia, MO, USA (2012); Visiting Professor in Department of Foods and Nutrition, The University of Georgia, GA, USA (2011 – 2012); Visiting Professor in Division of Endocrinology and Metabolism and Lipids, Department of Medicine, Emory University School of Medicine, GA, USA (2007 – 2011); Professor in Laboratory of Endocrinology and Molecular Metabolism, Graduate School of Nutritional Sciences, University of Shizuoka, Japan (1993 ~ August 2007); Associate Professor in Graduate School of Nutritional Sciences, University of Shizuoka, Japan (1991~1993); Assistant Professor in School of Pharmaceutical Sciences, University of Shizuoka, Japan (1987~1991); Visiting Assistant Professor in The University of Texas Medical School at Huston, USA (1988); Assistant Professor in Shizuoka College of Pharmacy, Japan (1986~1987); Visiting Assistant Professor in Texas Tech University School of Medicine, USA (1985); Visiting Lecturer in The University of Pennsylvania School of Medicine, USA (1981); Research Associate in Shizuoka College of Pharmacy, Japan (1973 ~ 1986). He received a Ph.D. in Pharmaceutical Sciences from Shizuoka College of Pharmacy (1976, Japan). He has completed his B.S. in Pharmaceutical Sciences, Shizuoka, Japan (1971). Dr. Yamaguchi is engaged in the fields of bone and calcium endocrinology and cell calcium signaling since 1971, and these researches are developed in the aspect of biochemistry, molecular biology, endocrinology, metabolism, nutrition, pharmacology, and toxicology. Dr. Yamaguchi has an interesting for cell signaling mechanism, bone biology, nutritional factor and osteoporosis prevention, diabetic osteoporosis, and cancer bone metastasis and osteolysis. Moreover, Dr. Yamaguchi discovered two novel proteins and genes; cell signaling suppressor protein (named regucalcin; 1978) and transcriptional factor RGPR-p117 (regucalcin gene promoter region-related protein; 2001) in mammalian cells. Dr. Yamaguchi generated regucalcin transgenic rats, which were registered as international patents (USA, EU, Japan, and Korea), and this animal is found to induce osteoporosis and hyperlipidemia. Recently, Dr. Yamaguchi proposes that regucalcin is a target molecule in carcinogenesis of various cancer cell types. Currently, the research of regucalcin is focused as a scientific topic. Dr. Yamaguchi published over 500 English articles to professional journals with peer-review. In addition, Dr. Yamaguchi registered over 20 national and international patents in the fields of his research interesting. Dr. Yamaguchi is serving as editors and editorial board members of reputed 40 international Journals. He received many honor and awards; Prize for Sato Memorial Fundation (1992, Japan/USA), Senji Miyata Foundation Award 2005 (Japan), Japan Society for Biomedical Research on Trace Elements Award 2007, The Lifetime Achievement Award from International Biographical Centre (IBC) (2004, England), The World Lifetime Achievement Award from American Biographical Institute (2004, USA), The Distinguished Service to Science Award from IBC (2007, England), and many others. Dr. Yamaguchi is listed in various biographies; Who’s Who in the World (2005-, Marquis Who’s Who, USA), Who’s Who in Sciences and Engineering (2004-, Marquis Who’s Who, USA), International Biographical Dictionary (2006-, IBC, England), and others.

 Biography
Research Interest :

Dr. Yamaguchi is engaged in the fields of bone and calcium endocrinology and cell calcium signaling since 1971, and these researches are developed in the aspect of biochemistry, molecular biology, endocrinology, metabolism, nutrition, pharmacology, and toxicology. Dr. Yamaguchi has an interesting for cell signaling mechanism, bone biology, nutritional factor and osteoporosis prevention, diabetic osteoporosis, and cancer bone metastasis and osteolysis. Moreover, Dr. Yamaguchi discovered two novel proteins and genes; cell signaling suppressor protein (named regucalcin; 1978) and transcriptional factor RGPR-p117 (regucalcin gene promoter region-related protein; 2001) in mammalian cells. Dr. Yamaguchi generated regucalcin transgenic rats, which were registered as international patents (USA, EU, Japan, and Korea), and this animal is found to induce osteoporosis and hyperlipidemia. The research of regucalcin is focused as a scientific topic. Dr. Yamaguchi published over 500 English articles to professional journals with peer-review. In addition, Dr. Yamaguchi registered over 20 national and international patents in the fields of his research interesting.

 Research Interest
 Network
Smita Mohanty

Executive Editor
Smita Mohanty

Associate Professor
Department of Chemistry
Oklahoma State University
United States
Phone: (405) 744 6636
E-mail: Smita.Mohanty@okstate.edu
Web: chemistry.okstate.edu/mohanty
Read Interview session with Smita Mohanty

Biography :

Dr. Smita Mohanty received her doctoral degree in Chemistry in 1988 from University of Delhi in India. She conducted postdoctoral studies in University of Washington, Seattle, WA and in New York in Structural Biology.

 Biography
Research Interest :

Research Interests:

Structure-function studeis of both membrane and soluble protiens having critical biological function
High-resolution NMR spectroscopy and protien crystallography for protien structure determination
Computational chemistry for modelling, docking and small molecule library screening
Protien-ligand interaction studies by biochemical and biophysical methods
Molecular Biology including cloning and mutagenesis
 

 Research Interest
 Network
Kennedy S. Wekesa

Executive Editor
Kennedy S. Wekesa

Alabama State University
USA
 

Biography :

Dr. Kennedy S. Wekesa received his BS in Biology from Guilford College, MS in Biology from the University of North Carolina Greensboro and his Ph.D. in Zoology from North Carolina State University under the direction of Dr. John G. Vandenbergh. His graduate work focused on the role of pheromones in regulating reproductive behavior and physiology. After his graduate work he did his postdoctoral research on signaling mechanisms in the vomeronasal organ under the direction of Dr. Robert H.Anholt at North Carolina State University. He is currently employed at Alabama State University where he is the Associate Dean for the College of Science, Mathematics and Technology and Professor of Biology. His lab studies signaling in the vomeronasal system and the roles of pheromones on behavior and physiology.

 Biography
Research Interest :

Signaling in the vomeronasal system, role of pheromones in regulating behavior and physiology.

 Research Interest
 Network
Wan Lee

Wan Lee
Department of Biochemistry
College of Medicine
Dongguk University
Gyeongju, Korea
 

Biography :
 Biography
Research Interest :

Molecular Mechanisms Involved in Diabetes, Metabolic Syndrome, Mitochondrial Dysfunction-related Diseases

 Research Interest
 Network
Md.Salahuddin

Md. Salahuddin,

PhD Fellow
Faculty of Medicine
University of Hongkong
Hongkong
Read Interview session with Md.Salahuddin

Biography :

DR. Md. Salahuddin is an immunophysiologist from Bangladesh. He is now working as  Faculty of Medicine at University of Hongkong, Hongkong. He obtained Doctor of Veterinary Medicine and MS in Physiology from Bangladesh Agricultural University. He has been working on immunophysiology of dendric cell and its role in cancer biology. His MS theses were involved in understanding effects of Protein, vitamin and probiotics in Animal health and diseases. He elucidated mechanism of the exact level of protein for the highest production of broiler weight. He has awarded a fellowship from National science and Technology Ministry of Bangladesh for his outstanding research (2011). Md participated in many international scientific seminars and symposium.

 Biography
Research Interest :

Immune-physiology, Dendritic cell, cancer and herbal medicine

 Research Interest
 Network
Sanjoy Chakraborty

Sanjoy Chakraborty
The City University of New York
USA

Biography :

Sanjoy Chakraborty
Associate Professor
College of Technology
Department of Biological Sciences
The City University of New York
Brooklyn, New York, 11201-2983, USA
Tel. 718-260-5968

 Biography
Research Interest :
 Research Interest
 Network
Gao Nan

Gao Nan
The State University of New Jersey
USA

Biography :

Instructor, Department of Genetics, University of Pennsylvania
Postdoc, Department of Genetics, University of Pennsylvania,
Visiting Scholar, University of California, San Francisco
Ph.D., Cell and Developmental Biology, Vanderbilt University
M.S., Shanghai Medical School, Shanghai, China
Bachelor in Medicine, Soochow Medical School, Suzhou, China
 

 Biography
Research Interest :
 Research Interest
 Network
Robert H. Broyles

Robert H. Broyles
University of Oklahoma Health Sciences Center
USA

Biography :

Robert H. Broyles, Founder and President of The Sickle Cell Cure Foundation, earned a BS (chemistry) and PhD (biochemistry) from Wake Forest University and its Medical Center and obtained post-doctoral training with a National Institute of Health fellowship from Florida State University. Dr. Broyles served five years as an Assistant Professor of Zoology at the University of Wisconsin-Milwaukee and 34 years of professorships in the College of Medicine at the University of Oklahoma. His current appointments are Professor of Biochemistry & Molecular Biology and Professor of Pediatrics (Adjunct) at the University of Oklahoma Health Sciences Center (OUHSC). Dr. Broyles has served as Senior Scientist at the National Institutes of Health in the Hematology Program and the Laboratory of Chemical Biology of NIDDK, as a Lecturer in the Embryology Course of the Marine Biological Laboratory in Woods Hole, Massachusetts, and as Research Member of the Free Radical Biology & Aging Research Program at the Oklahoma Medical Research Foundation.
 

 Biography
Research Interest :

Regulation of gene expression as applied to sickle cell disease, malaria, cancer, neurological & cardiovascular diseases, diabetes
Organ culture techniques, especially as applied to liver
Stem cell differentiation and molecular engineering by gene regulation therapy
Natural products & biological molecules as pharmaceuticals/nutraceuticals
 

 Research Interest
 Network
Cecilia Holloran Marzabadi

Cecilia Holloran Marzabadi
Seton Hall University
USA

Biography :

Dr. Cecilia H. Marzabadi received her Bachelor’s degrees (Chemistry and Biology) and Masters degree (Chemistry) from Saint Louis University She earned her Ph.D. in Chemistry at the University of Missouri- St. Louis. Her doctoral research examined the preparation and reactions of glucal halohydrins. Dr. Marzabadi did post-doctoral research at Hunter College/CUNY under the direction of Professor Richard Franck. Her post-doc project looked at the synthesis of 2-deoxysugars using a cycloaddition/ring opening based approach. In 1999, she was appointed as a Clare Boothe Luce Assistant Professor in chemistry at Seton Hall University. She was promoted to Associate Professor in 2005.  In 2006, she was a Visiting Associate Professor at Harvard Medical School in the lab of Dr. Dennis Kasper studying the innate immunology of a novel class of zwitterionic saccharide. Dr. Marzabadi has been the Associate Chair and Director of Graduate Studies for her department at Seton Hall since 2009.

 Biography
Research Interest :

Dr. Marzabadi’s current research interests lie in several areas of synthetic carbohydrate chemistry. Ongoing projects in her lab include:  the synthesis of septanose C-glycosides and septanose sugars by a ring-opening/ homologation/ ring-closing strategy. Methods are also being developed for the synthesis of simplified analogs of zwitterionic sugars to be studies in immunological assays. Small molecule therapeutics are also being developed from carbohydrate beased-heterocycles. An iodoamidation procedure has been developed for the synthesis of carbohydrate-based oxazolines to be studied as glycosidase inhibitors. A Povarov reaction has been used to construct novel carbohydrate-based quinolines for study as anti-cancer and antibiotic agents. Novel cyclopropanated sugars and glycals have been developed that display efficacy in the treatment of epilepsy and chronic pain management

 Research Interest
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Jingshi Shen

Jingshi Shen
University of Colorado
USA

Biography :

I trained as a molecular and cell biologist in graduate school at Columbia University, where I worked with Dr. Ron Prywes to study the ER stress regulation of ATF6, a membrane-tethered transcription factor activated by ER-Golgi transport and intramembrane proteolysis. During this period, my interest in membrane transport grew stronger. This ultimately prompted me to join Jim Rothman’s laboratory as a Jane Coffin Childs Postdoctoral Fellow to address more fundamental issues in membrane trafficking. A pioneer in membrane biology, Jim discovered a number of central components of membrane transport including SNAREs, NSF and the COPI coat. While in Jim’s group, I addressed long-standing problems in neurobiology and cell biology regarding Sec1/Munc18 (SM) protein function and fusion specificity. In October 2008 I joined the faculty of the University of Colorado-Boulder. 

 Biography
Research Interest :

We investigate the molecular mechanisms of regulated exocytosis using combined tools of biochemical reconstitution, biophysical analysis and cell-based transport assays.

 Research Interest
 Network
Sung-Kun Kim

Sung-Kun Kim
Baylor University
USA

 

Biography :

Hanyang University, Department of Chemistry, BS
Hanyang University, Department of Chemistry, MS
Texas Tech University, Department of Chemistry and Biochemistry, PhD
Texas Tech University, Department of Chemistry and Biochemistry, PostDoc
Baylor University, Department of Chemistry and Biochemistry, Assistant Professor
 

 Biography
Research Interest :

Drug Discovery using rational and combinatorial approaches (target enzymes: metallo-beta-lactamases, sulfonucleotidereductases)
Mechanism studies of redox proteins (APS reductases, glutaredoxins, thioredoxins, and arsenatereductase)
 

 Research Interest
 Network
Moorthy Krishnan

Moorthy Krishnan
Vanderbilt University
USA

Biography :
 Biography
Research Interest :
 Research Interest
 Network
Kevin Charles Kemp

Kevin Charles Kemp
University of Bristol
UK

Biography :

Dr Kevin Kemp is a researcher within the School of Clinical Neurosciences at the University of Bristol, UK. He read his first degree in Biomedical Sciences at the University of the West of England in 2003, where he went on to receive a PhD in 2007. Prior to his PhD studies Dr Kemp received a distinction for his Masters degree in Transfusion and Transplantation Sciences at the University of Bristol. As a senior post-doctoral scientist at the Multiple Sclerosis and Stem Cell laboratories, University of Bristol, his research interests are now in the therapeutic use of stem cells for neurodegenerative disorders, an area in which he has published many scientific research papers. Dr Kemp has a major role in supervising post-graduate students and clinical research fellows. He has also set up a number of research collaborations through close liaison with researchers from the around the world.

 Biography
Research Interest :

The aims of my current research are to explore new treatments for patients with degenerative ataxias and other neurodegenerative disorders. My research involves investigating the potential of mobilisation (drug induced or transplantation) of human bone marrow-derived stem cells and/or other stem cell populations to promote neuronal cell survival and regeneration.

 Research Interest
 Network
Yue Ge

Yue Ge
Integrated Systems Toxicology Division
National Health and Environmental Effects Research Laboratory
U.S. Environmental Protection Agency
Research Triangle Park
NC 27711 USA
 

Biography :

Dr. Ge received his Ph.D. at the University of Michigan, Ann Arbor, USA, where he investigated pathological and physiological mechanisms of Duchenn Muscular Dystrophy by identifying and characterizing disease targets, biomarkers and signaling pathways associated with the disease onset and progression using functional proteomic approaches.  Prior to his Ph.D. studies, he had worked in Walther Oncology Center, Indiana University for four years, where he studied cytokine gene expression in human stem and progenitor cells and gene therapy. Following the completion of his Ph.D. study, Dr. Ge moved to Department of Proteomics at Invitrogen, where he worked as a lead scientist for breast cancer proteomic project focusing on identification of breast cancer biomarkers using Multiplexed Proteomics Technology Platform built within the research team, and a project leader for development of protein assays for the detection and quantification of protein biomarkers.  In 2006, Dr. Ge took the position of Principal Investigator at US Environmental Protection Agency (EPA). His laboratory is working in the emerging field of toxicoproteomics for the development of toxicoproteomics methodologies and applications of the methodologies developed to systematic and high-throughput analysis of toxicity pathways and toxic mechanisms of environmental chemicals, and identification of protein toxicity signatures/biomarkers for human health risk assessment. His research efforts and publications have led to invitations to serve as conference chair and keynote speaker, OMICS session chairs for SETAC, EUROTOX, AES and several other international conferences. He is currently serving as North America Regional Editor for Journal of Integrated OMICS, and Associate Editor for Environmental Health and Toxicology. Dr. Ge is a recipient of multiple US biotechnology patents and EPA Scientific and Technological Achievement Award (STAA). He is currently leading an EPA’s Innovative research project on “Predictive Proteomic Risk Assessment of Chemical Mixtures”

 Biography
Research Interest :

Proteomics and its application to Environmental toxicity research; Chemical mixture toxicity, safety assessment and human health risk assessment; Environmental carcinogenesis research; Biomarker discovery and proteomics technology development; Stem cell biology.

 Research Interest
 Network
Yunfu Lin

Yunfu Lin
Assistant Professor
Department of Biochemistry and Molecular Biology
Baylor College of Medicine
USA

Biography :

B.A., Beijing Normal University, 1982
M.S., Beijing Normal University, 1985
Ph.D., Fudan University, 1993 

 Biography
Research Interest :

My research interest focuses on understanding the mechanisms of CAG repeat (CTG repeats on the complementary strand) instability using model systems in culture human cells and mice. Expansion of CAG repeat tracts within the human genome causes several neurological diseases such as Huntington's disease, myotonic dystrophy, and several spinocerebellar ataxias. However, the mechanisms leading to repeat instability, as well as disease pathogenesis, are ill-defined. The repeats are unstable in both germline and somatic cells, typically biased to expansion (increasing the number of repeats).

 Research Interest
 Network
Angel Manteca

Angel Manteca
University of Oviedo
Spain

Biography :

Dr. A. Manteca obtained the Biology degree from the University of Oviedo in 2000 and a PhD-degree in Microbiology, in 2005. After a postdoctoral stay at the University of Southern Denmark, working in quantitative mass spectrometry, he returned to the University of Oviedo as a postdoctoral researcher in 2011. Dr. Manteca has published more than 26 works in the most important microbiological and proteomic journals.

 Biography
Research Interest :

The main research line of Dr. Manteca is focused in the study of Streptomyces biology and differentiation. Streptomyces is a gram positive bacterium characterized by a complex developmental cycle, which is the evolutionary origin of some of the eukaryiotic signalling protein domains (apoptotic ATPases, kinases, caspases, nucleases, etc.). In addition, it is a very important industrial bacterium producing around two thirds of clinically relevant secondary metabolites. A. Manteca was pioneer in the application of new experimental methods to the analysis of Streptomyces biology.

 Research Interest
 Network
William H Konigsberg

William H Konigsberg
Professor
Molecular Biophysics and Biochemistry
Yale University
USA

Biography :

Dr. William H Konigsberg has received his Ph.D. in Organic Chemistry from Columbia University, N.Y. in 1956. Currently, he is working as Professor in Molecular Biophysics and Biochemistry at Yale University. He is serving as an editorial member of reputed journal Proteins: Structure, Function, and Genetics. He is a member of American Society of Microbiologists since 1984.

 Biography
Research Interest :

Blood Coagulation, DNA Replication,Genetics, Proteins and Macromolecules.

 Research Interest
 Network
Joseph Fomusi Ndisang

Joseph Fomusi Ndisang
Associate Professor
Department of Physiology
College of Medicine
University of Saskatchewan
Canada

Biography :

Joseph Fomusi Ndisang received postdoctoral training in Physiology at the University of Saskatchewan College of Medicine from 2000-2005. He received a PhD in Pharmacology & Toxicology from the University of Florence, Italy, 2000. He received a Doctor of Pharmacy degree from University of Florence, Italy in 1995. He has received several distinguished awards and distinctions including Fellow of the American Heart Association (FAHA) in 2011.

 Biography
Research Interest :

His research is mainly focused on investigation the role of the heme oxygenase system in hypertension, diabetes (types-1 and -2), and obesity.

 Research Interest
 Network
Justin W. Brown

Justin W. Brown
Department of Biology
James Madison University
USA

Biography :

Dr. Justin Brown received his PhD in Physiology from East Carolina University where he explored the role of the hypothalamus in the hypothermic response to hemorrhagic shock in rats.  His post-doctoral training at Dartmouth College focused on the role of brainstem serotonin on the thermoregulatory & cardiorespiratory responses to environmental stress during sleep in piglets as a model for Sudden Infant Death Syndrome (SIDS). He is now an associate professor at James Madison University in Harrisonburg VA where he teaches neuroscience & physiology/pathophysiology. He also maintains an active research program with graduate and undergraduate students, and collaborators at the US EPA (Chris Gordon PhD), in exploring the role of brainstem serotonin in the thermoregulatory and cardiovascular responses to exogenous stress in rats as a model for SIDS. His most recent work focuses on the role of ambient and/or preferred temperature in thermoregulatory stress and has implications in the wider field of animal care.

 Biography
Research Interest :

The role of brainstem serotonin in the thermoregulatory and cardiovascular responses to stress as a model for Sudden Infant Death Syndrome. The thermoregulatory responses to thermal stress in rodents – applications in animal care. 

 Research Interest
 Network
Padmanava Dash

Padmanava Dash
Department of Biology and the Environmental Science Ph.D. program
Jackson State University
USA

Biography :

Dr. Dash’s research interest includes water quality, Harmful Algal Blooms (HABs) and phytoplankton ecology, toxic metals, harmful microorganisms, remote sensing, limnology, biological and physical oceanography, and coastal and oceanic biogeochemical processes. HABs are caused by species of tiny plants, phytoplankton. HABs may cause harm through the production of potent chemical toxins or by their accumulated biomass. Due to the human health threats and their negative impact on aquatic life, recreation and tourism, HABs have significant economic and sociocultural impacts worldwide. Additionally, the freshwater systems are affected by eutrophication, leading to undesirable increases in harmful microorganisms (pathogens) and toxic metals. Dr. Dash’s current research interest includes field, laboratory and satellite remote sensing research to study various HAB forming species to enhance the current state of knowledge on detection and mapping of the HABs and thus support state and coastal community efforts to manage human health and fisheries in the region.

 Biography
Research Interest :

Coastal and Estuarine Ecology, Limnology, Environmental Toxicology, Remote Sensing, Harmful Algal Blooms, Biological Oceanography, Water Quality, Biological and Physical Oceanography and Coastal & Oceanic Biogeochemical processes.

 Research Interest
 Network
Thomas P. West

Thomas P. West, Ph.D
Professor and Head of the Department of Chemistry
Texas A & M University - Commerce
TX 75428, USA

Biography :

Dr. Thomas P. West received his PhD in Biochemistry at Texas A&M University in 1980. Dr. West is a Full Professor within the Department of Biology and Microbiology at South Dakota State University on the Brookings campus. He is currently serving as a member of 6 editorial boards. He has authored or coauthored 130 research articles.

 Biography
Research Interest :

His research interests are in the field of microbial biochemistry. His current research is investigating biomass-based specialty chemical production by microorganisms, microbial production of commercially important polysaccharide gums and the regulation of pyrimidine metabolism at the level of enzyme synthesis and enzyme activity in pseudomonads and related species.

 Research Interest
 Network
Vani Nilakantan

Vani Nilakantan, PhD
Director
Investigator-Initiated Sponsored Research
Aurora Research Institute
Milwaukee, WI 53234
USA

Biography :

Dr. Vani Nilakantan is the Director of Investigator-Initiated Sponsored Research at Aurora Health Care. She provides leadership over clinical research activities and ensure that research priorities are in alignment with Aurora Health Care’s mission and strategic priorities. Dr. Nilakantan has created effective collaborative partnerships with senior administrative leadership, clinical system leaders and medical staff and is responsible for developing research programs in partnership with academia and industry. In her role as Director of the Sponsored Programs Office, she has oversight over federal, state, industry and foundation grants. Dr. Nilakantan is an ad-hoc reviewer for Kidney International, British Journal of Urology, Neuroscience India, PPAR Research, Free Radicals in Biology and Medicine and is on the editorial board for Journal of Clinical Rehabilitative Tissue Engineering Research and BioMed Research International. Dr. Nilakantan has held leadership roles in institutional, local and national committees including the Wisconsin Network for Health Research, Aurora Medical Directors Research Council, Aurora Cardiovascular Research Committee, Cancer Clinical Leadership Research Subcommittee, Aurora- AUWMG Research Committee, Animal Care and Use Committee, Aurora- Conflict of Interest Taskforce, MCW -Admissions Committee, MCW- Co-Chair Program Committee Women’s Faculty Council, International Society of Heart and Lung Transplantation - Quality of Life Scientific Council.

 Biography
Research Interest :

Prior to joining Aurora Health Care, Dr. Nilakantan was an Assistant Professor of Surgery at the Medical College of Wisconsin (MCW) where she led a research program in ischemic acute kidney injury and renal protection in kidney transplantation. Her work has been funded by intramural and extramural funding from AHA and NIH. Her collaborations with other investigators have led to 3 grants, 29 peer-reviewed publications and numerous presentations at national conferences Her current research interests are in studying racial disparities in organ transplantation and in the identification of novel serum diagnostic and prognostic biomarkers in cardiac injury and acute kidney injury. She is collaborating with investigators at UWM College of Health Sciences (Informatics) to develop tools and algorithms for building a clinical decision support module at Aurora Health Care for risk stratification of acute kidney injury. To this end, she and the investigators are UWM are submitting grants to national agencies in a joint manner.

 Research Interest
 Network
Ajay Singh

Ajay Singh, Ph.D
Assistant Professor  of Oncologic Sciences
University of South Alabama Mitchell Cancer Institute (USAMCI)
USA

Biography :

Ajay Singh, Ph.D., is an Assistant Professor of Oncologic Sciences at University of South Alabama Mitchell Cancer Institute (USAMCI). Dr. Singh received a Master’s degree in Biotechnology from Aligarh Muslim University and graduated from the Devi Ahilya University, Indore, India. He completed a short post-doctoral fellowship in the Department of Biochemistry and Molecular Biology at University of Nebraska Medical Center, Omaha, Nebraska. He later attained a research faculty position in the same department, and joined USAMCI in 2009 as a tenure-track faculty. Studies in Dr. Singh’s laboratory have been supported through state and federal grants. He was awarded funds from State of Nebraska for two consecutive years (2007 and 2008) and one grant each from National Cancer Institute (NCI) and Department of Defense (DOD) to support his research. Dr. Singh serves on regional, national and international panels to review research proposals for funding considerations.

 Biography
Research Interest :

Major focus of Dr. Singh’s research is to delineate the molecular mechanisms underlying the aggressive and therapy-resistant behavior of cancer cells. In particular, his lab is investigating the role of microRNAs and tumor microenvironment in facilitating growth, epithelial to mesenchymal transition (EMT), metastasis and drug-resistance of pancreatic and prostate tumor cells. Earlier studies of Dr. Singh identified a mucin gene, MUC4, to be of pathological significance in pancreatic cancer progression and metastasis. MUC4 is an aberrantly expressed glycoprotein in pancreatic cancer exhibiting no expression in the normal pancreas. Recently, his team identified a novel microRNA-mediated mechanism involved in its deregulation in pancreatic cancer. Dr. Singh’s research has also revealed that CXCL12-CXCR4 signaling axis, an exemplary of tumor-microenvironment interaction, promotes drug-resistance in pancreatic cancer cells. In additional studies, his group has identified protein phosphatase 2A (PP2A) as a novel therapeutic target in prostate cancer. They have shown that PP2A activity is inversely associated with androgen-independent growth of prostate cancer cells through a novel mechanism, whereby loss of PP2A-mediated checkpoints leads to the activation of Akt and ERK and partially sustains androgen receptor signaling under steroid-deprived condition. The findings from Dr. Singh’s lab offer potential therapeutic implications for microRNAs, PP2A and tumor-microenvironment in highly aggressive and therapy-resistant pancreatic and/or prostate malignancies.

 Research Interest
 Network
Bhagelu Ram Achyut

Bhagelu Ram Achyut
Post Doctoral Fellow
Department of Biochemistry and Molecular Biology
Cancer Center
Georgia Regents University
USA
Read Interview session with Bhagelu Ram Achyut

Biography :

I am a postdoctoral fellow in Cellular and Molecular Imaging Laboratory, Radiology, Henry Ford Health System, MI. Current goal is to discover and alter the signature miRNAs in tumor cell secreted exosomes to reprogram the microenvironment and control neovascularization in glioblastoma. I completed Ph.D. (2009) in the Department of Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, India. I investigated association of genetic polymorphisms of cytokines and other inflammatory molecules with human gastritis and precancerous gastric lesions. Later, I joined Indian Institute of Toxicology Research, India as a scientist in 2008.I joined laboratory of Cancer Biology and Genetics, NCI-NIH for advanced postdoctoral training in 2009. I investigated inflammation mediated alterations could drive cancer development upon stromal abrogation of TGFβ signaling. My research was published in PLoS Genetics and highlighted in Nature Reviews of Cancer Journal. This experience allowed me to gain laboratory skills and a solid foundation in basic science research.

 Biography
Research Interest :

Cancer Biology (Anti-angiogenesis in Glioblastoma), Cancer Biology and Genetics (Anti-inflammation in Squamous cell carcinoma of the Forestomach), Neurotoxicology (Manganese nanoparticle induced neurotoxicity in rat), Medical Genetics (Role of cytokine gene polymorphisms in human gastritis susceptibility), Biotechnology

 Research Interest
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Kenneth Maiese

Kenneth Maiese
Head of Translational Medicine and External Innovation
Professor, Chair, & Chief of Service, Neurology and Neurosciences
Rutgers-New Jersey Med School
New Jersey, USA

Biography :

Kenneth Maiese is Head of Translational Medicine and External Innovation, and past Professor, Chair, and Chief of Service of the Department of Neurology and Neurosciences at Rutgers. He graduated from the University of Pennsylvania Suma cum Laude with Distinction, was a Teagle and Grupe Scholar at Weill Cornell Medical College, and trained as a physician-scientist at the NIH. Dr. Maiese has received outstanding teaching awards and election to Americas Top Physicians, the Best of U.S. Physicians, and Top Doctors. He is a top cited author with continuous funding from multiple agencies such as the American Diabetes Association, the American Heart Association, the Bugher Foundation, and the NIH. Dr. Maiese holds several patents, has over 350 publications and has authored 5 books. Dr. Maiese also serves as the Editor-in-Chief, Associate Editor, or editorial board member for more than 80 journals as well as on multiple executive, technology, and scientific advisory councils.

 Biography
Research Interest :

translational drug development, oxidative stress, cell signaling, transcription factors, apoptosis, autophagy, biomarkers, growth factors, metabotropic receptors, cancer, stem cells

 Research Interest
 Network
Qun Wang

Qun Wang
Assistant Professor
Department of Chemical  and  Biological  Engineering, 
Department  of  Civil,
Construction and Environmental Engineering,
Iowa State University
USA

Biography :

Dr. Qun Wang works as assistant professor with a joint appointment in the Department of Chemical and Biological Engineering and the Department of Civil, Construction and Environmental Engineering at Iowa State University, as well as associate scientist at the Ames National Laboratory of Department of Energy. He got his Ph.D. in Chemical and Petroleum Engineering from University of Kansas in 2010. He also got another Ph.D. in Environmental Science and Engineering from Wuhan University in 2007. Before he joined Iowa State University, he has worked as Jorge Heller Postdoctoral Fellow in Professor Robert Langer’s Lab at MIT and Harvard Medical School. He serves as Associate Editor of Journal of Biomedical Nanotechnology and Editorial Board Member of International Journal of Pharmaceutics.

 Biography
Research Interest :

Dr. Wang’s areas of interest include Biomaterials, Intestinal Engineering, Nanotechnology, and Drug Delivery. In Iowa State University, Dr. Wang BINDs his research in these areas to provide innovative solutions and products for human health. His current research focuses on developing functional materials for biomedicine. Functionalized design represents a powerful strategy for developing next generation materials for numerous emerging applications, including energy, pharmaceutics, environment and medicine. Dr. Wang will employ his multidisciplinary expertise in materials science, stem cells, microfabrication, and pharmaceutical chemistry to address and resolve the challenging problems of public health.

 Research Interest
 Network
Deepak Kumar

Deepak Kumar
Associate Professor of Biology
Chair, Department of Biology, Chemistry and Physics
Co-Director, UDC Cancer Research and Education Academy
Cancer Research Laboratory       
University of the District of Columbia
Washington DC 20008

Biography :
 Biography
Research Interest :

Molecular basis of Cancer Prevention, MicroRNAs in Prostate Cancer, Molecular Mechanisms of Apoptosis, Biomarkers for early cancer detection and target for drug development, Cancer Health Disparity

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Vikas Bhat

Vikas Bhat
Post-doctoral scholar
Dept of Medicine
University of California
San Diego
USA

Biography :

Dr. Vikas Bhat received his PhD degree in Biochemistry and Molecular Biology from University of Miami, Florida, USA. His thesis was mainly focused on understanding the mechanism of interaction and functional characterization of apoptotic repressor protein BclXL. He primarily devoted his study on finding the novel in-vitro properties associated with this protein which were previously not understood. Using a diverse array of biophysical methods (such as microcalorimetry, light scattering and optical spectroscopy including transient measurements) in conjunction with other in silico, protein biochemistry and molecular biology techniques to decipher the mechanism of action of the BclXL apoptotic repressor. In particular, his work has provided new insights into the ability of BclXL to assemble into highly-ordered amyloid-like fibrils with length in the order of mm and a diameter in the um-range under elevated temperatures. Strikingly, the BclXL fibrils appear to be optimally primed for insertion into cardiolipin bicelles, implying that they likely represent an on-pathway intermediate for insertion into mitochondrial outer membrane during the onset of apoptosis. During his PhD, he published many first author and coauthor papers focused around elucidating novel biophysical and biochemical properties of proteins involved in regulating many important pathways in a cell. Currently working at the University of California, San Diego as a post-doctoral scholar, Dr. Bhat is actively involved in finding novel protein based therapeutics for regulating blood loss in hemophilia and various other diseases related to coagulation pathway.

 Biography
Research Interest :

Proteomics, Structural Biochemistry, Molecular Biophysics, Cellular Signaling, Homeostasis and Drug Discovery

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Zhou J. Deng

Zhou J. Deng
Postdoctoral Researcher at MIT
Massachusetts Institute of Technology
Cambridge

Biography :

Dr. Jason Deng is an Early Career Research Fellow awarded by the National Health and Medical Research Council, Australia in 2013. Since 2011, Jason has joined Massachusetts Institute of Technology as a postdoctoral researcher, working with Professor Paula Hammond at Koch Institute for Integrative Cancer Research. Jason received his PhD in biomedical sciences at the University of Queensland, Australia in 2011with distinction of Dean’s award in research excellence.

 Biography
Research Interest :

Jason’s research has been focusing on the interdisciplinary field of Nano-Biosciences: investigating the interactions of nanomaterials with biological systems, developing new type of cancer therapeutics using nanotechnology, and promoting translation of benchtop research to bedside medicine. His work involves nanomedicine, drug and siRNA delivery, combination therapeutics development, nanotoxicology, cell-based assay development for drug discovery, biomarker discovery and cancer diagnostics. Jason published as the first author in prestigious journals such as Nature Nanotechnology, ACS Nano, and Nanotoxicology; while his collaborative work has been published in Lancet, Advanced Materials, Advanced Healthcare Materials and Scientific Reports.

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Kamil Kuca

Kamil Kuca
Research and Development,
Department of Chemistry,
Faculty of Science,
University of Hradec Kralove,
Hradec Kralove,
Czech Republic

Biography :

• Research and Development, Department of Chemistry, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech Republic (since 2013)

• Head, Center for Transfer of Biomedical Technologies, University Hospital, Hradec Kralove, Czech Republic (since 2012) • Head, Biomedical Research Center, University Hospital, Hradec Kralove, Czech Republic (since 2011)

• Vice-Dean for Research - Faculty of Military Health Sciences, University of Defense, Hradec Kralove Czech Republic (2009-2012)

• Research and Development at the Centre of Advanced Studies, Faculty of Military Health Sciences, University of Defense, Hradec Kralove, Czech Republic (2006-2009)

• Lecturer at the Department of Chemistry, Faculty of Sciences, J.E. Purkinje University, Usti nad Labem, Czech Republic (2006-2012)

• University teacher and Research fellow at the Department of Toxicology, Faculty of Military Health Sciences, University of Defense, Hradec Kralove CZ (2001-2006)

 Biography
Research Interest :

Military toxicology; Acetylcholinesterase reactivators as treatment of nerve agent and pesticide intoxications; Acetylcholinesterase inhibitors in Alzheimer´s disease and Myasthenia Gravis treatment; Synthesis of the detergents as disinfectants, decontamination means and environment for micellar catalysis; Drug design and Development; Chemical warfare agents; Biological warfare agents; Pharmaceutical Industry; Project Management; Scientific Management; Technology Transfer; Commercialization; Toxins.

 Research Interest
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Mingjie Chen

Mingjie Chen
Senior Research Scientist
University of Missouri
Columbia
United States

Biography :

I was born in a rural village of central China, and I spent my childhood there until I was 15. My parents are farmers, but only had a small piece of land for food production due to the land reform and population explosion. My parents areilliteracy, but they gave his kids chance to go to public schools for education.After school I helped my parents for various chores. My parents survived the “Great hunger” which happened at late 1950s in China;I can’t image how they managed to raise up our four siblings. Their stories of struggle to survival deeply influenced me. Although I left that land that brought me up, I can’t stop thinking what I could do to help those that still live like my parents, which inspired me to a journey of plant science research.

 Biography
Research Interest :

My long-term research interest is to understand the biochemical and molecularbasis underpinning various traits that plants gained during their evolutionary history, and apply this knowledge to crop species for improved growth performance, higher yield, and better quality. Currently, my research covers two major topics: 1) The metabolic mechanisms that affect seed composition, storage reserve accumulation or remobilization; 2) The biochemical and molecularbasis of plant tolerance to abiotic stress (cold, freezing, heat and draught stress etc.), especially the membrane lipid desaturation for plant stress response. To address the complexity of these biological questions of interest, various traditional and emerging new techniques will be applied, these include but not limit to genetics, biochemistry, molecular biology, physiology, –omics-based system biology and statistical modeling.

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Hiroyuki Hirai

Hiroyuki Hirai
Department of Genetics,
Cell Biology and Development
Stem Cell Institute
University of Minnesota
Minneapolis, USA

Biography :

Dr. Hirai, Research Associate of Genetics, Cell Biology and Development at the University of Minnesota, is an investigator of the Stem Cell Institute and the Minnesota Supercomputing Institute. He received his Ph.D. in Biochemistry from Tokyo Medical and Dental University. He studied muscle stem cell biology and therapy at Stem Cell Institute, University of Minnesota as a postdoctoral fellow. He then studied biochemical analysis of nuclear remodeling in somatic cell nuclear cloning. Recently he fused the transactivation domain (TAD) of MyoD to the pluripotency gene Oct3/4 and radically improved the efficiency of making iPSCs. In addition, fusion of the MyoD TAD to the cardiac transcription factor Mef2c facilitates the direct reprogramming of non-cardiac fibroblasts to cardiomyocyte-like cells.

 Biography
Research Interest :

Dr. Hirai's current research interests are to develop a transdifferentiation strategy and stem cell biology. These studies are expected to contribute to the development of celluar/gene therapy and regenerative medicine. He has been investigating progenitor cells, somatic stem cells and induced pluripotent stem cells (iPSCs) of mouse and human. He continues the research of other regulators necessary for the direct reprogramming and iPSCs reprogramming.

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Divya Patel

Divya Patel, Ph.D
Center for Cancer Research and Therapeutic Development
Clark Atlanta University,
Atlanta, Georgia

Biography :

Dr. Divya Patel received her Master’s in Microbiology and Ph.D. in Biochemistry from The Maharaja Sayajirao University of Baroda, Baroda, India. She then moved to USA to pursue postdoctoral research at Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL where her work focused on generating RNA Aptamers against immunotherapeutically important target molecules belonging to the tumor necrosis factor (TNF) receptor super family. Dr. Patel is currently continuing her postdoctoral training at Clark Atlanta University’s Center for Cancer Research and Therapeutic Development (CCRTD) and her research concentrates on exploring the role of members of bHLH family of transcription factors in prostate cancer development and progression.

 Biography
Research Interest :

My research focusses on human medicine with the goal of identifying key disease (specifically cancer) mechanisms and targets. With this aim, my current research work concentrates on exploring the role of members of bHLH family of transcription factors, specifically E2A (TCF3) in prostate cancer development and progression. E2A is known to regulate transcription of target genes by homo- or heterodimerization with other bHLH proteins such as MyoD, Mash, NeuroD and Id family of helix loop helix proteins. In general, E2A promotes cell differentiation, acts as a negative regulator of cell proliferation in normal cells and cancer cell lines and is required for normal B-cell development. Given the diverse biological pathways regulated/ influenced by E2A little is known about its expression in prostate cancer. My project therefore involves trying to investigate the mechanism of regulation of E2A in prostate cancer which could either be epigenetic or by gene fusion and chromosomal translocations or androgen receptor dependent. I was also involved in generating RNA Aptamers against immunotherapeutically important target molecules belonging to the tumor necrosis factor (TNF) receptor super family such as OX40 (CD134, TNFRSF4) and 4-1BB (CD137, TNFRSF9). Aptamers are single stranded oligonucleotides capable of binding to their target molecules with high affinity and specificity. They are derived by a process called SELEX (Systematic Evolution of Ligands by EXponential enrichment). Unlike monoclonal antibodies, aptamers have low molecular weights, are chemically synthesized and non immunogenic. Thus, aptamers can serve as promising probes for molecular recognition for diagnostic and therapeutic purposes.

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Gregory Lee

Gregory Lee
UBC Center for Reproductive Health
University of British Columbia
Vancouver, Canada

Biography :

Upon completion of his Ph D degree in Biophysical Chemistry at California Institute of Technology in 1972, he joined UCSD as a NIH Postdoctoral Fellow to carry out pioneer work on general ligand affinity chromatography. In 1976, he studied enzymology and biochemical genetic at the National Institute of Health and in 1981, he was appointed as a faculty member and director of the Andrology Laboratory at the University of British Columbia. During the last two decades, he has created numerous monoclonal antibodies for diagnostic and therapeutic applications in human health care, including RP215 and GHR106 for potential use as anti-cancer drugs.

 Biography
Research Interest :

Research and Development of Antibody-Based Anti-Cancer Drugs

- RP215 monoclonal antibody was shown to recognize specifically a carbohydrate-associated epitope located on the variable regions of cancer cell expressed immunoglobulins, designated in general as CA215.

- Structural elucidation of carbohydrate-associated epitope in CA215 which is recognized by RP215 monoclonal antibody (Mab)

- Humanizations of RP215 Mab for preclinical studies

- Generations of Rat anti-idiotype Mabs as candidates for the development of anti-cancer vaccines in humans

- Establishment of an Anti-GnRH receptor Mab, GHR106, as a substitute of short-acting GnRH analogs for antibody-based anti-cancer drugs, as well as preclinical studies.

- Elucidation of mechanisms of action for RP215 and GHR106 as antibody-based anti-cancer drugs.

- Elucidation of a carbohydrate-associated epitope recognized by RP215 monoclonal antibody.

 Research Interest
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Amol Suryawanshi

Amol Suryawanshi
Department of Ophthalmology
Tufts University School of Medicine
Boston, MA

Biography :

Dr. Suryawanshi received his DVM degree from Bomaby Veterinary College, India and MS in Biochemistry from Indian Veterinary Research Institute, India. He then completed his PhD in Comparative & Experimental Medicine at the College of Veterinary Medicine, The University of Tennessee. His doctoral research work focused on understanding the role of IL-17A and Th17 cells in herpes simplex virus 1-induced corneal immunopathology. As a postdoctoral research fellow at Tufts University School of Medicine, he is studying the role of host innate and adaptive immune response in mediating corneal pathology and vision impairment against various microbial infections of the cornea.

 Biography
Research Interest :

Host Pathogen Interaction and associated immunopathology. Infectious Blindness, Angiogenesis, Inflammation, Corneal Immunopathology, Infectious Diseases. Identifying novel molecular and cellular targets for pharmacological intervention of inflammatory conditions.

 Research Interest
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Pankaj Sharma

Pankaj Sharma
Postdoctoral fellow
Center for cancer research and therapeutic development
Department of Biological Sciences
Clark Atlanta University
Atlanta, GA
 

Biography :

Pankaj Sharma is currently working as a postdoctoral fellow since 2009, at center for cancer research and therapeutic development; Atlanta, GA. Interest in oncology research moved her from California to Georgia. Her first postdoctoral fellow position was in children’s hospital Oakland research institute, CA.There she worked on vaccine development of Chlamydia trachomatis. Although her first postdoctoral fellowship was for short period but she learned lot about protein research which influenced her towards the field of proteomics. Her recent research work is based on protein- protein interaction study of bHLH transcriptional regulators and study the effect of this interaction on Androgen signaling pathway in prostate cancer. She finished her doctoral degree (in Genetics with minor in biochemistry) from Chaudhary Charan Singh Haryana Agricultural University, India. Being from an agricultural state, her doctoral research work is based on the genetics and biochemistry of soil micro-organisms, which helps cultivated crops under drought stress conditions and can be used as a biofertilizers.She also received a university scholarship/award for this research program. She also served as a research associate in same university and then she moved to US, to explore the field of molecular biology. Personal interest includes cooking, traveling and music.

 Biography
Research Interest :

To understand molecular events where in a differentiated cell becomes undifferentiated, bypasses senescence, undergoes immortalization and eventually becomes transformed. By integrating a multitude of molecular, proteomic and genomic approaches to address the fundamental biology of these events that eventually leads to neoplastic transformation. The model systems that we use to address these molecular pathways are prostate cancer. Also how Id proteins helps in renewal and maintenance of stem cells. Interested in protein structural studies

 Research Interest
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Graziano Pinna

Graziano Pinna
Department of Psychiatry
University of Illinois
Chicago
Office Phone: 312-355-1464
E-mail:gpinna@psych.uic.edu 

Biography :
 Biography
Research Interest :

mouse models of post-traumatic stress disorder (PTSD); investigating the mechanism of action of antidepressants; developing new efficacious therapies for anxiety disorders and PTSD

 Research Interest
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Rammohan Devulapally

Rammohan Devulapally
Postdoctoral Research Fellow
Department of Radiology
Stanford University
California

 

Biography :

Rammohan Devulapally received his Ph.D. in Synthetic Organic Chemistry from Department of Chemistry, National Chung Cheng University, Taiwan in 2009, under the guidance of Prof. Yung-Son Hon. His Ph.D. thesis work focused on TiCl4-promoted intramolecular cyclization reactions and their application in the total synthesis of natural products. After his PhD, he worked with Prof. Chung-Chen Liao as a postdoctoral fellow in Chung Yuan Christian University on masked ortho-benzoquinones (MOBs) and azulene chemistry in organic synthesis. Then, he moved to Texas A&M University at Qatar as a postdoctoral research associate, worked on synthesis and cross-coupling reactions of organotrifluoroborates with Prof. Dave Seapy and Prof. Gary Molander. Presently, he is working with Dr. Paulmurugan as a postdoctoral research fellow in Molecular Imaging Program at Stanford (MIPS) and Bio-X Program in Stanford University School of Medicine. His current research work focus on developing multifunctional polymer nanocarriers for the co-delivery of therapeutic microRNAs and drugs for hepatocellular carcinoma (HCC) and triple negative breast cancer treatment in pre-clinical small animal model. He is serving as an expert reviewers for journals like, The Journal of Organic Chemistry, Tetrahedron Letter, International Journal of Nanomedicine, and Biochemical Pharmacology. He has authored several research articles in journal like Tetrahedron Letter. WIREs Nanomedicine and Nanobiotechnology and Journal of Organic Chemistry. He is a member of American Chemical Society and World Molecular Imaging Society (WMIC).

 Biography
Research Interest :

His current research interests are applications of synthetic organic chemistry to bioorganic, medicinal chemistry, chemical biology, nanomedicine and biomedical research.

 Research Interest
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Amit Kumar Tyagi

Amit Kumar Tyagi
Department of Experimental Therapeutics,
The University of Texas MD
Anderson Cancer Center,
USA
 

Biography :

Dr Amit Kumar Tyagi received his PhD degree in Applied Microbiology from Indian Institute of Technology Delhi, New Delhi, India where he studied the antimicrobial potential of different phytochemicals against food spoiling and disease causing microorganisms in in-vivo and in-vitro food models. During his PhD, he was awarded for European grant ‘Erasmus Mundus Corporation Window’ for doing part of his thesis work in University of Bologna, Italy. His work at The university of Texas MD Anderson Cancer Center revealed that TNF exhibit pro-inflammatory activities and may mediate carcinogenesis through the activation of a transcription factor NF-κB. The gene products regulated by NF-κB have now been linked to cellular transformation, tumor cell survival, proliferation, invasion, angiogenesis, metastasis, chemoresistance, and radioresistance. Mostly carcinogens, tumor promoters, growth factors, inflammatory agents, chemotherapeutic agents, radiation, viruses, bacteria, cigarette smoke, alcohol and other life style factors activate NF-κB and another transcription factor STAT3. Dr Tyagi’s research group is working on safe and multi-targeting chemopreventive agents derived from natural resources suppress NF-κB and STAT3 pathway and suppress tumorigenesis.

 Biography
Research Interest :

Study of transcription factors NF-kappaB and STAT3 signaling pathway, death receptor pathway, extrinsic and intrinsic pathway of apoptosis, anticancer properties of natural compounds in both in vitro and nude mouse models, study of cell cycle by flow cytometry, study of oxidative stress in animal models, antioxidants, study of genotoxicity by chromosomal aberration and micronuclei assay, study of gene expression by using western blotting and RT-PCR, DNA binding assay by EMSA, reporter gene expression, Immunohistochemical analysis, studies on both in vivo and in vitro experimental models, SEM, TEM, AFM, Food Microbiology and Food Chemistry.

 Research Interest
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Prem Kumar Sinha

Prem Kumar Sinha
Department of Biochemistry and Molecular Biology
Penn State College of Medicine
USA
 

Biography :

I am a PhD in Biochemistry and Molecular Biology with specialization in Biophysical chemistry and Enzymology from University of Bielefeld, Germany. I have 7 years of postdoctoral experience and 4 years of doctoral experience in Biochemistry, Bioenergetics, Enzymology and Biophysics. I also serve as a reviewer to many reputed journals in these areas, such as Biochemistry (ACS publications), Molecular and Cellular Biochemistry (Springer science), FEBS Journal, Protein & Peptide Letters, BMC Cancer and others.

 Biography
Research Interest :

Bioenergetics, iron-sulfur cluster(s), Enzymology, Electron Paramagnetic Resonance (EPR) spectroscopy, biophysics, osmolytes.

 Research Interest
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Shah Alam Khan

Shah Alam Khan
Associate Professor
Oman Medical College
Muscat, Oman
Read Interview session with Shah Alam Khan

Biography :

Dr. Shah Alam Khan is currently working as an Associate Professor of Pharmaceutical Medicinal Chemistry in the department of Pharmacy at Oman Medical College, Muscat, Oman (affiliated to West Virginia University, USA He received his Ph.D. from Jamia Hamdard University, New Delhi, in 2003 for studying role and chemistry of Silybum marianum, silymarin and its synthetic analogues in the hepatoprotection. He is also recipient of Government of India, Junior research fellowship (JRF, GATE) and Senior Research fellowship (SRF, CSIR) for pursuing masters and doctorate. He has published/presented more than 50 research articles in the national and international journal of repute. He is editorial board member of many international journals and has reviewed scientific papers in field of Pharmacy and science for more than 20 journals. He has supervised 15 undergraduate and post graduate research projects, two of them were awarded first and second prize in poster presentation category at international conferences. He has been invited as guest speaker in many conferences. He was awarded ‘Best Teacher’ in Pharmacy at Oman Medical College for the academic year 2010-11 and 2011-12 consecutively. He is life member of many professional bodies such as IPA, IPGA and APTI.

 Biography
Research Interest :

Synthesis and biological activity of Medicinal compounds of pharmaceutical interest

Chemistry and Pharmacological evaluations of natural products for antihepatotoxic, antidiabetic, antiinflamatory and anticancer activities.

Pharmaceutical analysis of drugs.

 Research Interest
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Basilio Vagner

Basilio Vagner
Private practice
Medellin Poblado Clinic
Colombia

Biography :

I am a clinical neurologist,in the city of Medellin Colombia; I work in research and care of patients with multiple sclerosis. I have a master in multiple sclerosis. I am coordinator of multiple sclerosis and demyelinating disease in the institution medicate. I am a teacher ingeneral neurology in medical schools and university Pontificia Bolivariana University of Antioquia,in the area ofundergraduateand graduate studentstointernal medicine,psychiatry,and neurology currentlyI haveseveral publicationsinbasic and clinical sciences

 Biography
Research Interest :
 Research Interest
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Sacide Pehlivan

Sacide Pehlivan
Istanbul University, İIstanbul Faculty of Medicine
Department of Medical Biology
Capa - Fatih / ISTANBUL
Office: 0 212 6351168
GSM Tel: 0 532 5231835
E-mail: sacide.pehlivan@istanbul.edu.tr; psacide@hotmail.com

Biography :

Assoc.Prof.Dr. Sacide Pehlivan  has received his PhD  in Department of Medical Biology of Hacettepe University during the period of 1992-1997.  Currently, she is working as Assoc.Prof.Dr. in Department of Medical Biology and Genetics of Medical Faculty of Gaziantep University. She has successfully completed his Administrative responsibilities as both teacher and researcher. She is serving as an editorial member of several reputed journals like Acta Oncologica Turcia, Journal of Paediatrics, Turkish Clinics... She has authored  88 research articles. She is a member of Eurepean Human Genetics, Turkish Medical Genetics, Turkish Medical Biology and Genetics.... She has honoured as 13 prizes.

 Biography
Research Interest :

Sacide Pehlivan’s interests  include  Molecular Medicine that represents diagnosis and prenatal diagnosis of human inherited diseasea and molecular mechanisms of different types of cancer and different human disease ( multiple sclerosis, nephrotic syndromes, vitiligo).

 Research Interest
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Yang Shun-Fa

Yang Shun-Fa
Director
Clinical Cancer Research
Chung Shan Medical University Hospital
Taiwan
E mail: ysf@csmu.edu.tw
 

Biography :

Yang is a professor of Institute of Medicine, Chung Shan Medical University, Taiwan. He has received the Ph.D. degree in molecular biology. In particular, his researches have been focused on pharmacology, cancer metastasis, cancer biology, genetic polymorphism and environment risk factors in cancer.

 Biography
Research Interest :

pharmacology, cancer metastasis, cancer biology, genetic polymorphism and environment risk factors in cancer

 Research Interest
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Syed Saleem Husain

Syed Saleem Husain
Department of Medical Chemistry
Faculty of Applied Medical Sciences
Jazan University
Kingdom of Saudi Arabia

Biography :

Dr Syed Saleem Husain aka Saleem Saim, age 48, is an Assistant Professor in Medical Chemistry Division, Faculty of Applied Medical Sciences, Jazan University, Jazan, Saudi Arabia. He completed his PhD from Industrial Toxicology Research Center, Lucknow, India, as a Research Fellow, in a project on Neurobehavioral Toxicity of Cadmium in relation to protein malnutrition, sponsored by Indian Council of Medical Research, New Delhi, India. He also holds a master degree in English language and has edited and authored many books. He is a widely acclaimed English poet and writer, published by his pen-name “Saleem Saim”. He has recently published a book entitled, ‘Chemical Studies on Toxic Effects of Cadmium’, published by Lambert Academic Publishing, Germany and a research paper “Studies on Hepato and Renal Toxicity of Cadmium on Normal and Protein Malnourished Rats”, Syed Saleem Husain, J. of Material Sciences & Engineering, 2013, 2-3”, (http://dx.doi.org/10.4172/2169-0022.1000129). He is a reviewer of refereed journals and researcher in the field of heavy metal toxicology.

 Biography
Research Interest :

Techniques on Neurotoxicology, Neurosciences, Applied Science, Toxic Effects of Heavy Metals on Human Brain, Material Sciences and Engineering, Neurobehavioral Impact of Protein Malnutrition, Industrial Toxicology

 Research Interest
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MOHAMMED KUDDUS

MOHAMMED KUDDUS
Associate Professor
Department of Biochemistry
College of Medicine
University of Hail
Hail
Kingdom of Saudi Arabia

Biography :

Dr. Mohammed Kuddus completed his PhD in Biotechnology from SHIATS, Allahabad, India in 2007. He has joined Department of Biotechnology, Integral University, India as an Assistant Professor and currently working as an Associate Professor at College of Medicine, University of Hail, Saudi Arabia. Dr. Kuddus’s main research area includes microbial enzymes and protein biotechnology. He has published more than 30 research articles in the national/international journals along with 3 book chapters; and presented more than 35 abstracts in the national and international conference/symposia. Also, he has supervised 5 PhD and 10 MSc students for their thesis/dissertation. He is serving as an Editorial Board Member of various national and international journals as well as reviewers for more than 20 international journals. He has been awarded Young Scientist Projects from International Foundation for Science, Sweden, and Department of Science and Technology, India; and CSIR-SRF and IBRO fellowship. He is an active member of various national and international scientific associations.
 

 Biography
Research Interest :

• Enzyme and Fermentation Technology
• Biochemistry
• Microbial Biotechnology

 Research Interest
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Kavish Ramessur

Kavish Ramessur
Researcher
SSR Medical College 
Belle Rive, Mauritius

Biography :

I am certified in Biostatistics and Epidemiology from Harvard Medical School with over a dozen research publications in reputed Medical Journals. I have also authored four medical books – two of which are research theses and two are Textbooks of Biochemistry for Medical Students. The latter have received international acclaim and are being used as standard texts in Medical Schools worldwide. I also am the webmaster of “Biochemistry for Medics,” a non-profit website aimed at making Biochemistry more accessible to medical students; a site that receives over five thousand visitors every day. My field of expertise is “Oxidative Stress” which I feel, is at the root of several pathologies and whose curtailment shall open new vistas towards newer therapeutic approaches.

 Biography
Research Interest :
 Research Interest
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Seema Jawalekar

Seema Jawalekar
Sree Narayana Institute of Medical sciences
India

Biography :

Seema Jawalekar
Associate Professor
Sree Narayana Institute of Medical sciences
Chalakka, Ernakulam, India
 

 Biography
Research Interest :

My areas of interest are  Kidney diseases, metabolic disorders, Molecular biology, cardiovascular diseases

 Research Interest
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Banudevi Sivanantham
Drug Delivery lab, Centre for Nanotechnology and Advanced Biomaterials (CeNTAB),
India



Biography :

Dr.Banudevi Sivanantham received her B.Sc (2000) in Biochemistry and M.Sc in Biochemistry (2002) from University of Madras, as well as M.Phil (2004) in Endocrinology and Ph.D (2011) in Biochemistry-Endocrinology from Dr.ALM Post graduate institute of basic medical sciences, University of Madras. She also served as lecturer (2011-2012) in Valliammal College for Women, University of Madras, India for teaching biochemistry subjects for under and post graduates. She is currently postdoctoral fellow scientist in SASTRA University, Tanjore, India. Her areas of research interest include oral and prostate oncology, cell signaling pathway, stem cell technology, cross talk signaling, combinational treatment strategy and Drug delivery system. She is also has hobbies such as hand crafting, throw ball, shuttle cock and music. She was born in 1980 in Chennai, India

 Biography
Research Interest :

1) Investigation of multiple cell signaling pathway involved in oral and prostate cancer
2) Eludicate the cross-talk signaling pathways and cancer biology
3) Combinational strategy for treatment of oral cancer and prostate cancer
4) Drug delivery system and oral cancer

 Research Interest
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Mohammad Najafi

Mohammad Najafi
University of Medical Sciences
Tehran

Biography :

Dr. Mohammad Najafi received his PhD in Clinical Biochemistry during the period of 2002-2006. He joined the Iums faculty in 2008. Since coming to Iums, he has developed Bioinformatics in the Biochemistry zone in Medical Sciences. He currently teaches postgraduate students the applications of Bioinformatics databases and tools in your researches in Tehran University of Medical Sciences since Iums is merged with Tums. Its researches are focused on phatobiogenesis of atherosclerosis. Moreover, he has focused on the quality control techniques in clinical investigations

 Biography
Research Interest :

Biochemistry, Molecular genetics, Bioinformatics

 Research Interest
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Zainab Mahmood Aljamali

Zainab Mahmood Aljamali
Assistant Lecturer Prosthodontics
Dentistry department
University of Babylon, IRAQ.
Tel: 009647817340558
E-mail: Zainab.jouid@yahoo.com
 

Biography :

I am Dr. Zainab Mahmood Aljamali. I have Certificate in 2012, in prosthodontics, Dentistry. I have papers publication (4) articles in (prosthodontics and physiology).

 Biography
Research Interest :

prosthetic dentistry, dentistry treatment, biochemistry, Medicine field

 Research Interest
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Abdel-Aziz Fatouh Abdel-Aziz

Abdel-Aziz Fatouh Abdel-Aziz
Faculty of Science,
Mansoura University, Mansoura,
P.O.Box 35516, Egypt

Biography :

- 2009 –until now, Professor/consultant of Biochemistry, Faculty of Science, Mansoura University, Mansoura, Egypt.

- 2009 – until now, Director of University Development Center, Mansoura University, Egypt.

- Responsible for teaching academic courses for undergraduate and postgraduate students, examination, training the graduating students during summer training period, research projects,research supervision, consulting the students cultural activities and quality assurance program in Chemistry and Biochemistry.

- Co-coordinator of Biochemistry program, Faculty of Science, Mansoura University.

- Supervisors of many Masters and P.hD. theses in Biochemistry.

- Author of more than 40 papers

- Membership of Egyptian biochemistry and molecular Biology Society.

- Membership of Egyptian Chemical Society.

- Membership of American Chemical Society

 Biography
Research Interest :

Water and Mineral metabolism, Applied, cellular and clinical biochemistry, Practical courses in biochemistry, Drug metabolism and drug-drug interaction, Advanced metabolism, Free radical and antioxidants in health and diseases, Hormones and signal transduction and related disorders, Lipids and lipoproteins disorders, Inborn error of metabolism

 Research Interest
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Mahmoud Balbaa

Mahmoud Balbaa
Department of Biochemistry
Faculty of Science
Alexandria University
Egypt
Read Interview session with Mahmoud Balbaa

Biography :

Professor of Biochemistry, Beirut Arab University, Lebanon. Professor (2009–up to date).

Head of Department of Biochemistry, Faculty of Science, Alexandria University, Egypt (2007–2009).

Professor of Biochemistry, Faculty of Science, Alexandria University, Egypt (1999–2002; 2006-2009) and University of Qatar, Doha, State of Qatar (2002–2006).

Assistant Professor of biochemistry, Faculty of Science, Alexandria University, Egypt (1994–1999).

Lecturer of biochemistry, Faculty of Science, Alexandria University, Egypt (1988–1994). 

 Biography
Research Interest :

The study of enzyme inhibition by newly synthesized structures for the establishment of biologically active compounds important for drug design or medicinal chemistry.

The study of enzymatic variation and some signaling pathways in some diseases such as Diabetes mellitus.

The characterization of the enzyme in patients and healthy individuals is studied in a whole investigation of biomarkers of a parasitic or hereditary disease.

The detection of the biochemical changes occurring is parasitic diseases such as schistosomiasis and faschioliasis by studying the characterization of many different enzymes in these diseases. This includes the study of enzymes involved in biological oxidation and cell signaling.

 Research Interest
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M. Rajajeyakumar

M. Rajajeyakumar
Assistant Professor
Department of Physiology
CHENNAI MEDICAL COLLEGE HOSPITAL & RESEARCH CENTER
IRUNGALUR
TRICHY
Tamilnadu
India

Biography :

Dr. M.Rajajeyakumar, MBBS, MD, MSc Yoga, CCEBDM (PHFI), PhD, is working as Assistant professor of Physiology at Chennai medical college hospital & research Centre (SRM Group) Trichy, Tamilnadu, India (Affiliated by Dr MGR Medical University, Chennai). He received MBBS degree from Tirunelveli Medical College and completed MD Physiology, under the guidance of Dr.Madanmohan & Dr.J. Balachander (2006-2009) at Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER- An Institution of National Importance under the Ministry of Health & Family Welfare, Govt. of India). He has been teaching Physiology for more than five years after obtained his Master Degree. Then he worked as a senior resident (2009-2012) in the same department and research assistant in Advanced Centre for Yoga Therapy, Education & Research (ACYTER) Lab, JIPMER, collaboration with Morarji Desai National Institute of Yoga (MDNIY). He did MSc yoga in Annamalai University and completed ISAK (International Society for the Advancement of Kin anthropometry Level 1 & 2 in the year of 2010-11). He had completed the Basic Course on ECG Interpretation (2013) from Dr.Chenniappan’s ECG & ECHO Club of Trichy and Evidence Based Diabetes Management (CCEBDM), under Public Health Foundation of India (PHFI), which was recognized by international Diabetic Federation (IDF) at Trichy diabetic centre (Dr.Shanmugavelu and Dr.Bosco) in the year of 2013-14.

Dr. M.Rajajeyakumar has been actively involved in research. His special research experience is in Yoga, autonomic, cognitive, cardio-respiratory, neurophysiology and medical education. He had trained with basic Physiological procedures including human and animal experimental physiology; pulmonary function test (PFT), autonomic function test (AFT), HRV (heart rate variability), EMG (electromyography), & NCS (nerve conduction study) related research. He has published many papers in reputed national & international journals. He is a life member of many national and international journals and scientific bodies. He is an expert reviewer and editorial board member for many national and international journals.He has been selected for Examiner and Question paper setting for various medical, paramedical & biomedical engineering under and post graduate courses.

He is one of the resource person in Medical Education Unit for conducting basic Programme on Medical Education Technologies for faculties. He is the in charge of representative for ISO-9001& active members of writing systematic operating procedure (SOP). Recently, he has been appointed as Staff Advisor & Programme Co-ordinator of Youth Red Cross Society of Chennai medical college hospital & research Centre (SRM Group).

 Biography
Research Interest :

• Neurophysiology • Cardio- respiratory physiology • Exercise physiology • Psycho-Neuro-immunology • Neuro-endocrinology. • Yoga • Obesity & Aging • Psycho – cardiology • Medical education • Sleep & Nutritional studies • High altitude Physiology • Diabetes & Hypertension • Biomedical engineering

 Research Interest
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Sudheer Kumar Gara

Sudheer Kumar Gara
Postdoctoral Fellow
Endocrine Oncology Branch
National Cancer Institute
National Institutes of Health
USA

Biography :

Dr. Gara obtained his triple major’s Bachelor’s degree in Chemistry, Botany and Zoology from Andhra Pradesh, INDIA. He did his Master’s in Biotechnology and Bio-Engineering from one of the premier institutes in INDIA, the Indian Institute of Technology – Kanpur. He then moved to the University of Cologne, Germany with an international research fellowship to pursue his doctoral studies in functional genomics and genetics. Since 2011, he is currently pursuing his postdoctoral studies at the National Cancer Institute, National Institutes of Health, Bethesda. From 2011-2013, he identified the role the TGF beta mediated signaling in myeloid derived tumor suppressor cells in breast cancer metastasis. Later, I moved to the Endocrine Oncology Branch, within the NCI and actively involved in identifying and characterizing the genes that are associated with familial non medullary thyroid cancer and other cancer types. In addition, he was actively involved in the projects that aim to identify novel diagnostic biomarkers (particularly metabolites) in Urine and Serum samples of thyroid cancer patients. Dr. Gara is passionate and very much dedicated to contribute the best of his effort and his expertise to provide a better life for the patients suffering with cancer.

 Biography
Research Interest :

Cancer signaling, Immunotherapy, Structure based drug designing, Pharmacokinetics, Genetics and Functional Genomics

 Research Interest
 Network
Dr. A. Heidari

A. Heidari
Postdoctoral Research Fellow
Faculty of Chemistry
California South University (CSU)
Irvine, California
USA

Biography :

Dr. A. Heidari, Ph.D., D.Sc. is a Postdoctoral Research Fellow in Chemistry. He has got his Ph.D. and D.Sc. degrees form California South University (CSU), Irvine, California, USA. Furthermore, he has double postdocs in Project Management and also in Nanochemistry and Molecular Structure Theory. His research interests are Biophysical Chemistry, Nanochemistry, Quantum Chemistry, Biomolecular and Vibrational Spectroscopy, Molecular Modeling and Structure, Theoretical, Computational and Mathematical Chemistry, Ab initio and Density Functional Methods. He has participated at more than fifty reputed international conferences, seminars, congresses, symposiums and forums around the world as yet. Also, he possesses many published articles in Science Citation Index (SCI)/International Scientific Index (ISI) Journals. It should be noted that he has visited many universities or scientific and academic research institutes in different countries such as United States, United Kingdom, Canada, Netherlands, Russia, France, Swiss, Germany, Sweden, Spain, Portugal, South Korea, China, etc. as research fellow, sabbatical and volunteer researcher or visitor heretofore. He has a history of several years of teaching for college students and various disciplines and trends in different universities. Moreover, he has been a senior advisor in various industry and factories. He is expert in many computer programs and programming languages. Hitherto, he has authored more than ten books in Chemistry. Syne, he has been awarded more than two hundreds reputed international awards, prizes, scholarships and honors. Heretofore, he has multiple editorial duties in many reputed international journals. Hitherward, he is a member of more than one hundred reputed international academic–scientific–research institutes around the world.

 Biography
Research Interest :

Biophysical Chemistry, Biomolecular Spectroscopy, Quantum Chemistry, Nanochemistry, Theoretical Chemistry, Mathematical Chemistry, Computational Chemistry, Vibrational Spectroscopy, Molecular Modelling, Ab initio & Density Functional Methods, Molecular Structure

 Research Interest
 Network
Dr. Shamim Ahmad

Shamim Ahmad
Cancer Center
Augusta University
Augusta, GA
USA

Biography :

Dr. Ahmad has extensive research experience in the field of Immunology, Biochemistry and cell signaling. The broad aim of his research is examination of cellular and molecular mechanisms differentially regulating the signaling of T cell subset signaling, function and survival. The aim of in depth examination of these signaling pathways is the development of strategies to selectively manipulate specific subsets to enhance the efficacy of immune therapies. Phosphoinositide 3-kinase (PI3K)-Akt signaling is important for the differentiation, proliferation, and survival of a variety of cells, including immune cells. Dr. Shamim Ahmad evaluated the anti-tumor efficacy of combinational immunotherapy based on model vaccine and PI3K isoform specific inhibitor. He demonstrates that this treatment leads to a profound inhibition of tumor growth. He showed that the potent therapeutic efficacy of treatment is mediated by i) enhancing number of the effector T cells infiltrating into the tumor that is facilitated and ii) the decrease Tregs. Thus, he provides a promising and translatable strategy that can enhance the overall efficacy of cancer immunotherapy.

 Biography
Research Interest :

His research is focused on development of combinational cancer immunotherapies, immune corrective strategies and investigation of cellular and molecular mechanisms involved in tumor-mediated immune suppression, and development of strategies to overcome that suppression.

 Research Interest
 Network
 
 
 
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