ISSN: 2168-9296

Cell & Developmental Biology
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Editorial Board

LU Da-Yong

Editor-in-Chief
LU Da-Yong
Associate Professor
School of Life Sciences
Shanghai University
PR China

Biography :

LU Da-Yong, oc/professor; ad/1288 Shangda Rd, 95-202, Shanghai200444, PR China; ed/ph D Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 2005, MS, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 1986, BS, Shanghai Medical University (Now Fudan University affiliated) in1982; He is working as an associated professor at School of Life Sciences, Shanghai University, Shanghai200444, PR China. Undergo the studies of cancer pathology, biochemistry pharmacology and clinical therapeutics from 1982 and some articles in AIDS and neural science.

 Biography
Research Interest :

cancer biology
pathology
treatment, origins of life and other field of science disciplines

 Research Interest
 Network
Qiang Xu

Executive Editor
Qiang Xu
Department of Biology
Abilene Christian University
USA

Biography :

Dr. Qiang Xu is an Assistant Professor of Biology at Abilene Christian University in Texas. He received his Ph. D. in Entomology, Cell and Molecular Biology from Auburn University. Dr. Xu has been working as a visiting scientist at the U.S. Department of Agriculture -Agriculture Research Service Knipling-Bushland, U.S. Livestock Insects Research Laboratory during summers of 2010 and 2011. He serves as an editorial board member and a reviewer for many journals. Dr. Xu has also received numerous honors and awards, including Jeffery P. LaFage Research Award from the Entomological Foundation, President’s Prize for the Outstanding Poster Presentation from the Entomological Society of America, and a mentorship for McNair Scholars Program funded by U.S. Department of Education. Recently, Dr. Xu was selected as the chair of the Judging Panel for the International Congress on Insect Neurochemistry and Neurophysiology (ICINN) Student Recognition Award in Insect Physiology, Biochemistry, Toxicology, and Molecular Biology.

 Biography
Research Interest :

Dr. Xu’s research focuses on molecular mechanisms of insecticide resistance in mosquitoes, gene expression and regulation of horn flies, epigenetic mechanisms of insecticide resistance in house flies, gene evolution in insects, functional genomics of insects, and transgenic insects.

 Research Interest
 Network
George Perry

George Perry
Dean of the College of Sciences
Semmes Foundation Distinguished Chair in Neurobiology
University of Texas
San Antonio, USA

Biography :

George Perry, Ph.D., is Dean of the College of Sciences and the Semmes Foundation Distinguished Chair in Neurobiology at the University of Texas at San Antonio. He obtained his Ph.D. from Scripps Institution of Oceanography in 1979 and received a postdoctoral fellowship in the Department of Cell Biology at Baylor College of Medicine where he laid the foundation for his observations of abnormalities in cell structures. Dr. Perry is distinguished as one of the top Alzheimer’s disease researchers with over 1,000 publications, one of the top 100 most-cited scientists in neuroscience and behavior, and one of the top 25 scientists in free radical research. He is editor for numerous journals and is editor-in-chief for the Journal of Alzheimer's Disease. Internationally recognized, he is a Foreign Correspondent Member of the Spanish Royal Academy of Sciences, the Academy of Science Lisbon, and a Foreign Member of the Mexican National Academy of Sciences. He is also a recent recipient of the National Plaque of Honor from the Republic of Panama Ministry of Science and Technology. Dr. Perry’s research is primarily focused on how Alzheimer disease develops and the physiological consequences of the disease at a cellular level. He is currently working to determine the sequence of events leading to damage caused by and the source of increased oxygen radicals along with routes to provide more effective treatment.

 Biography
Research Interest :

Alzheimer disease

 Research Interest
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Xuehua Xu

Xuehua Xu
Chemotaxis Signal Section
Laboratory of Immunogenetics
NIH/NIAID
12441 Parklawn Drive
Rockville, MD

Biography :

Dr. Xuehua Xu obtained her bachelor’s and master’s degrees in biology from Harbin Normal University, China, and her PhD in biotechnology from Tsukuba University, Japan. Starting in 2002, Dr. Xu was in postdoctoral training at the National Institutes of Health (NIAID/NIH), where she focused on developing and applying state-of-the-art imaging technologies to monitor the signaling network of GPCR-mediated chemotaxis in the model organism Dictyostelium discoideum. The interplay between computational simulation and experimental verification allowed her to identify new components and novel signaling pathways essential for chemotaxis. In 2006, she was recruited as an assistant professor at the Georgetown University School of Medicine. She further expanded her research from the model organism to mammalian neutrophils and breast cancer. In 2010, she was recruited to NIH as a staff scientist. Her research focuses on understanding the molecular mechanisms of GPCR-mediated chemotaxis in multiple systems and identifying new therapeutic strategies for inflammatory diseases and metastasis of breast cancer.

 Biography
Research Interest :
 Research Interest
 Network

Executive Editor
Jyotshna Kanungo
Principal Investigator
USFDA
National Center for Toxicological Research
USA

Biography :

After obtaining her Ph.D. from Utkal University, India, Dr. Kanungo served as an Assistant Professor at the Orissa University of Agriculture and Technology (India). She then pursued post-doctoral research at the University of Florida, Gainesville, with a Rotary Foundation International award. Dr. Kanungo has published a number of book chapters and 47 peer-reviewed papers, 37 of which are indexed in the PubMed. Following many years of service as a Research Scientist at the National Institutes of Health, Dr. Kanungo serves as an Investigator/Lead Scientist at the National Center for Toxicological Research, US Food and Drug Administration where she is leading a nationally recognized zebrafish research program.

 Biography
Research Interest :

Developmental Biology
Neuronal development/degeneration
Animal models of neurodegeneration
Cell signaling/Molecular biology
Pluripotent/stem cell biology (proliferation, differentiation, apoptosis)
Zebrafish and Xenopus Development (gene-knockdown and over-expression)

 Research Interest
 Network
Robert C. Sizemore

Robert C. Sizemore
Professor
Department of Biological Sciences
Alcorn State University
USA
Tel. (601) 877-6677

Biography :

Dr. Robert Carlen Sizemore Professor of Alcorn State University, Department of Biological Sciences. He received his Ph.D. (Medical Microbiology & Immunology) from University of Louisville School of Medicine. He is a member of American Association of Immunologists, International AIDS Society. He even participated in the development of an Immunotherapeutic for the treatment of AIDS that was taken through Phase 1,2 and 3 clinical trials.
 

 Biography
Research Interest :
 Research Interest
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Paul J. Higgins

Paul J. Higgins
Professor and Center Director
Center for Cell Biology and Cancer Research
Albany Medical College
Albany,New York
USA

Biography :

Paul J. Higgins received his Ph.D. degree in molecular biology from New York University in 1976. He joined the faculty of the Memorial Sloan-Kettering Cancer Center and the Cornell University School of Medicine in 1977, where he was a member of the program on cell biology/genetics and the program on molecular biology/virology. Dr. Higgins is currently a Professor and Director of the Center for Cell Biology and Cancer Research at the Albany Medical College in Albany, New York. He was the founding Vice President of the Albany Research Institute and currently serves on the Board of Directors. He has been the Chairman of National Institutes of Health and Department of Defense Review Panels, and received several prestigious awards including the Moyer Award and, most recently, the 2008 Excellence Award in Molecular Medicine. Dr. Higgins has been a member of several journal editorial boards, edited books on cancer biology, and published more than 200 peer-reviewed scientific papers.

 Biography
Research Interest :

Our research focuses on the molecular mechanisms underlying transcriptional regulation of the critical inflammation and fibrosis-promoting factor PAI-1 (plasminogen activator inhibitor-1; SERPINE1).  PAI-1 is a major effector of human fibrotic disease where it promotes the development of, and maintains, the inflammatory and angiogenic responses. Our group was the first to establish cell cycle transcriptional controls on the human PAI-1 gene, and the promoter sequences involved, and related these findings to mapping individual growth factor-responsive promoter elements. We also made major advances in defining the signaling cascade that impact PAI-1 transcription in human epithelial cells and discovered a new pathway of cross-talk between two classes of growth factor receptors (EGFR and TGF-R) in PAI-1 expression control.  Our current efforts focus on creation of molecular genetic "reagents", including PAI-1 oligonucleotide decoys, antisense constructs, silencing RNAs and microRNAs that target PAI-1 gene expression in the fibrotic stroma as well as in angiogenic endothelial cells. The molecular basis of PAI-1 transcription and the role of PAI-1 as a pro-survival factor and critical element in angiogenesis are, in fact, the focus of my long-running NIH-funded R01 grant.  Additional studies in my laboratory have implicated the EGFR as a signaling intermediate in the TGF- pathway. We established the mechanism for receptor cross-talk and published a series of papers detailing the trans-activation of the EGFR by TGF- through a pathway involving the signaling intermediates pp60c-src, caveolin-1, and the RhoA GTPase. In this highly-interactive network, TGF- stimulates pp60c-src to phosphorylate the EGFR leading to ERK-dependent phosphorylation of the transcription factor USF2 activating its target gene PAI-1; in the second arm of the cascade, TGF- activation of Rho-ROCK signaling via caveolin-1 down-regulates the Smad phosphatase PPM1A to maintain Smad-dependent co-activation of the PAI-1 gene. Collectively, these events are required to maintain PAI-1 expression in human epithelial and microvessel endothelial cells.

 

 Research Interest
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Vasiliy Galat

Vasiliy Galat
Feinberg School of Medicine
Northwestern University
USA

Biography :

Dr. Vasiliy Galat is an Assistant Professor in the Department of Pathology at Northwestern University Feinberg School of Medicine. He is also the director of the Childrens Research Center iPS and Human Stem Cell Core Facility.  In 1998, Dr. Galat earned his PhD in biology from the Russian Academy of Science and continued his studies at the Max-Delbruck Center for Molecular Medicine in Berlin. In 2005, the American Board of Bio-Analysis certified Dr. Galat as a High-Complexity Clinical Laboratory Director. He started his clinical research career at Reproductive Genetics Institute in Chicago, directed the IVF laboratories at the New England Medical Center, Boston, Women’s and Infant Hospital, Providence, and the Preimplantation Genetic Diagnosis Laboratory, Los Angeles. Dr. Galat has been working on establishing and directed differentiation of hESCs and iPSC lines. He was the first to develop and introduce the hESC lines harboring the mutations specific for human diseases.

 Biography
Research Interest :

Stem Cells, Human Embryonic Stem Cells (hESC), Stem cell lineages, Cellular programming and reprogramming: Induced Pluripotent Stem Cells (IPSC), Somatic Cell Nuclear Transfer (SCNT), Directed differentiation, Fertilization, Preimplantation embryo development, Preimplantation Genetic Diagnostics, Medical Genetics, Experimental Embryology.

 Research Interest
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Hengye Man

Hengye Man
Associate Professor
Department of Biology
Boston University
USA

Biography :

Dr. Heng-Ye Man is an Associate Professor in the Department of Pharmacology & Experimental Therapeutics at Boston University. He received his Ph.D. from Toronto University in 2001. He continued his research in the Department of Neuroscience at Johns Hopkins University as a postdoctoral fellow until 2005, when he joined the faculty at Boston University in the Biology Department. Dr. Man’s research focuses on: Regulation of glutamate receptor trafficking and turnover, and the role of glutamate receptor dynamics in synaptic plasticity, learning and memory; Neuron morphogenesis, including axon initiation, neuronal polarization and dendritic pruning; The cellular and molecular mechanisms underlying neurological disorders, including Angelman Syndrome, autism and Alzheimer’s disease. Dr. Man has authored research articles in journals including Nature, Science, Cell, Neuron, J of Neuroscience and PNAS.

 Biography
Research Interest :

Neuroscience, with expertise in synaptic transmission, synaptic plasticity, glutamate receptors, protein trafficking, ubiquitination, degradation, neuronal development and neurological diseases

 Research Interest
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Nobuaki Furuno
Associate Professor
Institute for Amphibiam biology
Graduate School of Science
Hiroshima University
Japan

Biography :

1978-1982 Department of Biology, Facuty of Science, Kyushu University Awarded the degree of BSc in Science 1982-1984 Department of Biology, Facuty of Science, Kyushu University Awarded the degree of MSc in Science for the thesis entitled “The change of the 40S rRNA precursor in Xenopus embyos”. Work supervised by Assistant Professor Kobayashi. 1984-1989 Department of Medical Science, Faculty of Medicine, Kyushu University. Awarded the degree of Phd in Science for the thesis entitled “Complete genomic sequence of a cell-cycle negative regulatory gene involved in the onset of chromosome condensation -The human RCC1 gene-“ Work supervised by Professor Nishimoto Research and professional experience 1989-1993 Research Assistant at the Institute of Molecular Biology, Kurume University, working with Professor Sagata 1994-2002 Research Assistant in the Department Biology, Facuty of Science, Kyushu University, working with Professor Sagata Between 1997-1999, Wellcome/CRC Institute, University of Cambridge, Cambridge, granted by Exchange program by Science Council of Japan- Royal Society and Novartis fund. Working with Janathon Pines. 2002-presen Division of Differentiation Mechanism, Institute for Amphibian biology, Graduate School of Science, Hiroshima University Membership of academic societies: Japanese Society of Molecular Biologists. Japanese Society of Developmental biologist, Zoological Society of Japan, Japanese Society for Biological Sciences in Space.

 Biography
Research Interest :

My research interests are cell biology, molecular biology, developmental biology and space biology. Especially, I study the regulation of the cell cycle, meiosis (molecular mechanism of oocyte maturation) and early cleavage (Why embryos perform the cell cycle as fast as somatic cell) and the effects of the hypergravity for the meiosis, early development and metamorphosis. The methods to analyze these them are molecular biology, cell biology and histlogy.

 Research Interest
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Xinghua Pan

Xinghua Pan
Research Scientist
Department of Genetics
Yale University School of Medicine
USA

Biography :

Xinghua Pan,PhD, MD, Research Scientist, and Single-cell omics laboratory chief at Yale University School of Medicine. Focusing on novel technology development for genome-wide functional studies for single cells, Dr. Pan has established up a series of new approaches for single cell analysis on genomics, transcriptomics, epigenomics and telomere length analysis. He has also been applying these technologies in combination with other platforms especially next generation sequencing in translational medicine and variants of biological systems related to stem cells, immune cells, neurons, genetic diseases and cancers. He has authored ~ 60 papers in PNAS, Cell, Nature, etc. and ~20 reviews/book chapters, with 6 biotech patents issued and 7 patents in pending. He contributed to a number of key projects/subjects supported by NIH (National Institute of Health) on human genome project, stem cell, and cancer. He was interviewed by PNAS– Journal Club (2013) and GEN -Exclusive News (2015) for his achievements on single cell technology.

 Biography
Research Interest :
 Research Interest
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Julie V. May

Julie V. May
Associate Professor
Biological Science
William Carey University
Hattiesburg
USA

Biography :

I have spent the last eight years teaching undergraduate courses in human sciences – the courses needed by premedical/dental/health professional/nursing students. It has been an absolute honor to watch these students develop the concepts and skills needed for acceptance and success in health related professional schools. Although I work at an institution that has a medical school, I really enjoy teaching at the undergraduate level. When I started graduate school, I felt underprepared for what was required of me on the research and presentation level. So I aim to incorporate these skills into my courses probably more so than many undergraduate professors, so that students will start their postgraduate education with an added advantage of vital research skills. Outside of education, I strive to have balance in my life. My husband and I have six children between us, and I have a successful food blog – which is probably my biggest hobby.

 Biography
Research Interest :

As a broad generality, my research has been in the area of aging and neurological disease. My early career revolved around assisting individuals with age- and trauma- related diagnoses with reestablishing independent living skills. In my field, I worked with individuals affected by a wide variety of neurological disorders. Then I researched the accelerated neurological aging that accompanies Alzheimer ’s disease, and the power of various antioxidants in slowing down this process. My research in this area extended across several models – from the molecular and cellular level all the way up to the whole organism. I followed that up with involvement in research in the field of human obesity and how caloric restriction could alter markers of disease as well as extend the life span.

 Research Interest
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Tony Jun Huang

Tony Jun Huang
Associate Professor
Pennsylvania State University
USA
Tel. 814-863-4209
Fax 814-865-9974

Biography :

Tony Jun Huang is an Associate Professor in the Department of Engineering Science and Mechanics at The Pennsylvania State University (USA). He received his Ph.D. degree in Mechanical and Aerospace Engineering from the University of California, Los Angeles (UCLA) in 2005, and his B.S. and M.S. degrees in Energy and Power Engineering from Xi’an Jiaotong University, Xi’an, China, in 1996 and 1999, respectively.  His research interests are acoustofluidics, optofluidics, and micro/nano systems for biomedical applications. He has authored/co-authored over 90 peer-reviewed journal publications and over 80 peer-review conference papers in these fields. He serves as Vice Chair of the American Society of Mechanical Engineers (ASME) Nanoengineering Council and chair of the ASME Society-Wide Micro/Nano Technology Forum. His research findings have been recognized with awards and honors such as the 2006 Rustum and Della Roy Innovation in Materials Research Award, a 2010 National Institutes of Health (NIH) Director’s New Innovator Award, a 2011 Penn State Engineering Alumni Society Outstanding Research Award, a 2011 JALA Top Ten Breakthroughs of the Year Award, and a 2012 Outstanding Young Manufacturing Engineer Award from Society for Manufacturing Engineering.

 Biography
Research Interest :

MEMS, NEMS, Bionanotechnology, Nanomaterials, BioMEMS/BioNEMS, Microfluidics,

 Research Interest
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Lifeng Wang

Lifeng Wang
Department of Health and Human Services
National Institutes of Health
USA

Biography :

Dr. Lifeng Wang has received his Ph.D. from Chinese Academy of Sciences. Currently he is working in National Institutes of Health, Department of Health and Human Services, USA. He has published multiple high-impact journal papers and has presented his research work in many international meetings. He provides editorial service for the journals and he has worked as reviewer for 15 journals in different disciplines of biology and biomedical sciences, such as diabetes, PLos one, Cell Biology International etc. Dr. Wang has broad research interests and now he is focusing on the transcriptional regulation of gene expression (Epigenetic regulation).

 Biography
Research Interest :

Cell and Developmental Biology, Epigenetics, Cell differentiation, Obesity and Diabetes, Cancer biology, Stem cells etc.

 Research Interest
 Network
Amit Singh

Amit Singh
Center for Tissue Regeneration and Engineering
University of Dayton
USA

Biography :

Amit Singh is an Assistant Professor at Center for Tissue Regeneration and Engineering at Dayton (TREND) in Department of Biology at University of Dayton. His research area is using fruit fly Drosophila melanogaster eye as a model to study organogenesis, Cell survival, regeneration and growth. His lab research focus is to understand genetic basis of cell survival and neurodegeneration in eye. He has been actively engaged in developing interdisciplinary course curriculum on math biology that transcends the border of conventional disciplines of science. He has been instrumental in providing CAPstone research experience opportunities to undergraduates in his laboratory.

 

 

 Biography
Research Interest :

Organogenesis
Genetic basis of axial patterning during organogenesis
Drosophila eye model to understand growth regulation during organogenesis
Birth defects in eye
Drosophila model of  human Neurodegenerative disorders
Gene regulation and mechanism of apoptosis during growth and development
Signaling in development and organogenesis

 Research Interest
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Yuqing Zhang
Department of Pathology and Laboratory Medicine
Weill Cornell Medical College
USA

Biography :

Dr. Yuqing Zhang got her PhD from Shandong University in 2005. Currently she is working in Weill Cornell Medical College. Dr. Zhang′s research interests include DNA damage/repair and cancer biology and therapy. Dr. Zhang has published more than 20 papers in high impact journals and has presented her work many times nationally and internationally. Dr. Zhang serves on the review panel and editorial board of several journals.

 Biography
Research Interest :

DNA damage′repair, cancer biology, cancer therapy, molecular biology, drug resistance.

 Research Interest
 Network
Zhe Han

Zhe Han
Division of Molecular Medicine and Genetics
Department of Cell and Developmental Biology
University of Michigan Medical School
USA
Tel. (734)-615-5210

Biography :

Dr. Zhe Han received his Ph.D. from the University of Michigan in the Rolf Bodmer lab where the fly heat was first established as a model for heart development and diseases. He then did his postdoc training at the UT Southwestern Medical center in the lab of Dr. Eric Olson, a pioneer for mammalian heart and muscle development. He established his own lab in the University of Michigan in 2006 and focused on the genetic control of Drosophila heart development. Dr. Han has published many high impact papers in the heart development field in journals like Science, PNAS and Development, and received multiple awards from the American Heart Association (AHA). The research of Dr. Han’s lab is funded by the NIH and the AHA. Dr. Han’s lab recently developed a genetic screen system for genes involved in renal functions in fly and established the fly as a new model for kidney diseases.

 Biography
Research Interest :

Congenital heart defects (CHD) are leading causes of birth defects in the world. Understanding the genetic control of heart development is the foundation for better understanding the disease mechanism of CHD.

 Research Interest
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Ahmed Naseem Khan

Ahmed Naseem Khan
Department of Anatomy
Weill Cornell Medical Centre
USA

Biography :

Dr. Ahmed did his previous education from pakistan and after completing ND from karach migrated to london England in 1974 and stayed there untill 1984. During this he had further training ion orthopaedics and participated in lecture both in London and in Paris beside orthopaedics also lectured in cellular proliferation in trauma and cellular response on trauma and its various adaptation.Cellular response has always been his favourite topics to talk and to build its association with active disease process.In 1984 migrated to USA and worked with Dr Swanson a world renowned surgeon who was nominated for the noble prize and did fellowship in Hand Surgery. Participated in lectures meeting and conferences, he settled In new york and working at Weild Cornell medical centre since 1906 as lecturer in Anatomy. He is actively involved in teaching, prosection and Plastination.
 

 Biography
Research Interest :

His research interest always lies in cellular adaptation of tissues and its manifestation.

 Research Interest
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David X. Liu

David X. Liu
Department of Neural and Behavioral Sciences
College of Medicine
Pennsylvania State University
USA

Biography :
 Biography
Research Interest :

The focus of Dr. David Liu laboratory is to understand the signaling mechanisms that control death and viability of neurons and cancer cells. Our work has established that silencing of E2F responsive genes are required for neuron survival and that apoptotic stimulation leads to activation of cell cycle elements that promote E2F de-repression and neuron death. Our studies have further demonstrated that E2F-responsive apoptotic genes are silenced by E2F4-p130-Suv39H1-HDAC complexes in unstressed neurons and that apoptotic stimulation leads to CDK-dependent phosphorylation of p130, which results in disassembly of the E2F4-p130-Suv39H1-HDAC complexes on promoters of repressed apoptotic genes. Among these de-repressed apoptotic genes are transcription factors B- and C-myb. Elevation of B- and C-myb induces pro-apoptotic Bcl-2 family member Bim, provoking neuron death. One direction of our future work is to identify other key apoptotic genes that are controlled by the E2F de-repression pathway in neurons. Our lab uses interdisciplinary approaches including cellular, molecular, genetic, and biochemical techniques to dissect the apoptotic mechanisms used by neurons and cancer cells and to isolate novel proteins critical for regulation of cell death in those cells. We also use the same techniques to investigate how neural stem cells, such as telencephalic neuroprogenitor cells, are maintained and what promote their differentiation and survival.

 Research Interest
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Aimin Liu

Aimin Liu
Department of Biology
Pennsylvania State University
USA

Biography :

Aimin Liu is an associate professor at the Pennsylvania State University, USA. He obtained his PhD from New York University Medical Center, studying the roles of fibroblast growth factors in midbrain and cerebellum development. He then received postdoctoral training under the supervision of Drs. Lee Niswander and Kathryn Anderson at the Sloan-Kettering Institute and made the discovery that the primary cilium regulates Gli transcription factor activation and proteolytic processing in the mouse. The research in his lab is now focused on the molecular mechanisms of cilia biogenesis and the regulation of the Hedgehog signal transduction in mammals.

 Biography
Research Interest :
 Research Interest
 Network
Yanming Wang

Yanming Wang
Department of Biochemistry and Molecular Biology
Pennsylvania State University
USA

Biography :

Dr. Wang received a bachelor degree in Biochemistry in Shandong University in 1994 and obtained a diploma in Developmental Biology from Shanghai Institute of Cell Biology of the Chinese Academy of Sciences in 1997. He then moved to the US and received a Ph.D. degree in Molecular, Cellular and Developmental Biology at the Iowa State University in 2001. In his Ph.D. thesis work, Dr. Wang found that the Drosophila JIL-1 kinase regulates dosage compensation of the male X-chromosome by phosphorylating histone H3 serine 10site. His interest has been in chromatin biology and histone modifications ever since. He joined Dr. C. David Allis as a postdoc to polish himself as a “histone code” miner for 4 years. In his own lab at Penn State, Dr. Wang has been studying histone and protein Arg citrullination among other endeavors. Most recently, he is developing anticancer drugs to turn on tumor suppressor genes.

 Biography
Research Interest :

Epigenetic histone modifications in cell differentiation and cancer

 Research Interest
 Network
Robert H. Broyles

Robert H. Broyles
Health Sciences Center
University of Oklahoma
USA

Biography :

Robert H. Broyles, Founder and President of The Sickle Cell Cure Foundation, earned a BS (chemistry) and PhD (biochemistry) from Wake Forest University and its Medical Center and obtained post-doctoral training with a National Institute of Health fellowship from Florida State University. Dr. Broyles served five years as an Assistant Professor of Zoology at the University of Wisconsin-Milwaukee and 34 years of professorships in the College of Medicine at the University of Oklahoma. His current appointments are Professor of Biochemistry & Molecular Biology and Professor of Pediatrics (Adjunct) at the University of Oklahoma Health Sciences Center (OUHSC). Dr. Broyles has served as Senior Scientist at the National Institutes of Health in the Hematology Program and the Laboratory of Chemical Biology of NIDDK, as a Lecturer in the Embryology Course of the Marine Biological Laboratory in Woods Hole, Massachusetts, and as Research Member of the Free Radical Biology & Aging Research Program at the Oklahoma Medical Research Foundation.

 Biography
Research Interest :

Regulation of gene expression as applied to sickle cell disease, malaria, cancer, neurological & cardiovascular diseases, diabetes. Organ culture techniques, especially as applied to liver. Stem cell differentiation and molecular engineering by gene regulation therapy. Natural products & biological molecules as pharmaceuticals/nutraceuticals.

 Research Interest
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Li Yao

Li Yao
Department of Biological Sciences
Wichita State University
Wichita, Kansas
USA

Biography :

After completing his bachelor degree of clinical medicine in Capital Medical University, Beijing in 1994, Dr. Yao was appointed resident doctor of surgery at the Beijing Chao Yang Hospital, Capital Medical University Hospital. After 3 years working as a surgeon he pursued a Masters in orthopaedics at the distinguished Beijing JiShuiTan Hospital, Peking University Medical Center. He also worked for one year after his Masters study as an orthopaedic surgeon in this hospital. In 2001, Dr. Yao went to UK to pursue a PhD in Biomedical science at the University of Aberdeen. He pursued his Postdoctoral research at National University of Ireland, Galway and Mayo Clinic, Rochester. In his postdoctoral work, he also travelled to EMPA federal laboratory in Switzerland to carry out the joint neural regeneration investigations. He started his current position as a tenure-track assistant professor in department of Biological Sciences, Wichita State University in 2011.

 Biography
Research Interest :

Electric fields guided brain neuron migration, spinal cord repair and regeneration and peripheral nerve repair and regeneration.

 Research Interest
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Peng Sun

Peng Sun
Assistant Research Specialist
Department of Biochemistry and Molecular Medicine
University of California
USA

Biography :

Dr. Sun earned his PhD degree in Molecular Cell Biology from Chiba University, Japan. He worked at Chiba University and then in the Department of Biological Chemistry, University of California, Irvine. Currently, he is working at the Department of Biochemistry and Molecular Medicine, University of California, Davis. His research has been published in multiple peer reviewed articles in high-impact journals, and he serves as a reviewer for many journals. His research interest is in multidisciplinary fields including cell macropinocytosis, neuronal differentiation, spermiogenesis and stem cells.

 Biography
Research Interest :

Cell signal transduction;Neuronal differentiation;Skin and mammary epithelial stem cell self-renewal and differentiation; Tissue development; regeneration and repair; Animal models for human diseases.

 Research Interest
 Network
Korkmaz Belliturk

Korkmaz Belliturk
Assistant Professor
Department of Soil Science and Plant Nutrition
Namik Kemal University
Turkey

Biography :

I graduated from Trakya University, Faculty of Agriculture, Department of Soil Science in 1996 as top student of the department. At the same year, I both started to MS in institute of natural and applied sciences in Trakya University and work as research assistant in Trakya University, Department of Soil Science. I worked as research assistant in the same department between 1996 and 2007. I am working as Assistant Professor in Namık Kemal University, Faculty of Agriculture, Department of Soil Science and Plant Nutrition since 2007. And then, I was assigned to lecture for one week each within the context of Erasmus teaching staff mobility at Trakia Democritus University in Greece in 2011 and at University of Technology and Life Sciences in Poland in 2013. I was assigned for 3 months between 11 July and 11 October at “the University of Vermont” in Vermont-USA to take a part in a project called “use of soil earthworms in agriculture”. I served as project head and researcher in 16 projects supported by Tübitak, Trakya University, Namık Kemal University, Bilecik Seyh Edebali University and Bozok University Scientific Research Projects Units. I have 85 articles on soil science, soil ecology, plant nutrition, soil fertility, soil chemistry, soil-water pollution, ecologic agriculture, soil earthworms and fertilization topics as research articles and papers presented in domestic and abroad scientific meetings. Also, 8 of them are the articles published in international periodicals cited by international science indexes (SCI). I won 12 months research scholarship at “The University of Vermont” in Vermont-USA for the second term of 2013 in the context of Tubitak 2219 International Postdoctoral Research Scholarship Program

 Biography
Research Interest :

Soil Productivity, Plant Nutrition, Soil and Water Pollution, Fertilization, Soil Ecology, Compost and Vermicompost

 Research Interest
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Liang Ge

Liang Ge
Molecular & Cell Biology
University of California
Berkeley

Biography :

Driven by a deep curiosity about the living creature, Dr. Ge directed his studies toward biological science. His research training began in the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences. There he conducted PhD work on establishing a cell model to study cholesterol absorption. Now Dr. Ge is a senior research fellow in Randy Schekman (the 2013 Nobel Laureate in Physiology or Medicine) lab in Department of Molecular & Cell Biology at University of California Berkeley, where he employs systematic biochemical and cell imaging approaches to dissect different intracellular trafficking events. Dr. Ge was a Human Frontier Science Program Fellow in 2012. Currently, he is a Jane Coffin Childs Foundation Fellow.

 Biography
Research Interest :

Autophagy is a catabolic process for bulk degradation of cytosolic components. It plays a fundamental role in intracellular quality control and material recycling as well as adaptation to multiple stresses. Misregulation of autophagy has been indicated in many human disorders including cancer, neurodegeneration and aging. A key feature of autophagy is the de novo formation of double-membrane vesicles, termed autophagosomes, by a substantial membrane investment from various endomembrane sources. Since its discovery more than 50 years ago, the mechanism accounting for the membrane mobilization to generate the autophagosome has been a mystery. Dr. Ge’s research interest is to functionally dissect the process of membrane mobilization from existing cellular pools for autophagosome biogenesis. He developed a functional assay which recapitulates multiple landmarks of autophagosome biogenesis regulation based on LC3 lipidation, a key early step in autophagy. He has used this reaction and a complete organelle fractionation scheme to identify a novel source of membrane template for lipidation the endoplasmic reticulum-Golgi intermediate compartment (ERGIC), a sorting station for cargo transport between the endoplasmic reticulum and the Golgi appratus. Dr. Ge is currently focusing on the molecular machineries involved in mobilizing membrane from the ERGIC for delivery to a nascent autophagosomal precursor.

 Research Interest
 Network
Eden Rebecca Padayachee

Eden Padayachee
Department of Neurochemistry
University of Gothenburg
Gothenburg,
Sweden

Biography :

Dr. Eden Rebecca Padayachee is currently a post-doctoral fellow at the Institute of Neuroscience & Physiology in Gothenburg, Sweden. She received her Ph.D in Medicinal Biochemistry from Rhodes University, South Africa and possesses over 5 years of experience in enzymology, amyloid-beta aggregation and biomarker discovery. The title of her dissertation was “biochemical mechanisms of Alzheimer’s disease.” She is a scientific discoverer and innovator and was commented on by a thesis examiner, who said off her “This candidate’s discovery could be very important in the Alzheimer’s field and may be the most impactful result of this work. She should be complimented on her methodological expertise and tenacity.” She was recently selected as one of the top 15 candidates out of 300 to attend a 5 day boot camp at the BioMed-X GmbH in Heidelberg, Germany, targeting tau-mediated neurodegeneration in Alzheimer's disease. Her objective is open up her own pharmaceutical company specializing in biomarker discovery, related to enzymes as biosensors and the use of nanovehicles e.g. endogenous protein or lipid based particles that have regenerative properties. Her hobbies include writing a book entitled “How to become a visionary and be your own catalyst for positive change right now”. She is a master at writing her own powerful quotations to inspire others to reach their full potential.  She has been personally invited as guest speaker at the Alzheimer’s Association, UK; International Woman’s Club, Sweden and neuroscience conferences in South Africa, Thailand, China, America and Denmark, resulting in the creation of a global knowledge hub in Alzheimer’s research and innovative therapeutic strategies.

 Biography
Research Interest :

Dr. Padayachee’s passion is ENZYMES! She absolutely loves figuring out enzyme mechanisms, catalysis, kinetics and their function. As a structural biochemist and enzymologist, she enjoys studying enzyme-ligand binding, by using a suite of computational docking software e.g. AutoDock. Biological thermodynamics, spectroscopy, spectrofluorimetry, surface plasmon resonance, electron microscopy are some of the techniques she has used in studying ligand binding phenomena. She strongly believes that enzyme-ligand binding is the basis for future drug discovery as how proteins bind and their subsequent conformational changes are the keys to unlocking the design of therapeutic agents to target protein misfolding diseases. Amyloid fibrils and neurofibrillary tangles are hall marks of Alzheimer’s disease. In her Ph.D thesis she developed new therapeutic strategies in the diagnosis of Alzheimer’s disease by investigating the potential of the enzyme nitric oxide synthase as a catalyst for amyloid fibril formation. She discovered that nanoparticles reverse amyloid fibril formation. Her current position as a post doctorate focused on identifying high density lipoprotein (HDL) particles in cerebrospinal fluid and its effect on reducing amyloid aggregation in AD. Amyloid beta and Tau has been found to interact and form a complex at the synapse. A small molecule inhibitor that prevents the formation of this complex is ideal. She would like to apply the use of endogenous HDL as a “disaggregating agent" to block this complex from forming in the first instance. Targeting the clearance of Aβ and Tau simultaneously affords a combination therapy approach that could be very promising in the field of AD. She believes that imagination is more creative than knowledge and enjoys stimulating innovative thought in young minds by encouraging scientists to step out of their comfort zone and seek challenges at the interface between academia and industry.

 Research Interest
 Network
Didi Chen

Didi Chen
Department of Microbiology,
University of Texas
Dallas,TX

Biography :

Dr. Didi Chen earned her Ph.D. degree in Cell Biology from Chinese Academy of Sciences in Beijing, China and then she worked at Massachusetts General Hospital, Harvard Medical School at Harvard University. Currently, She is working in the Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX. Her research has been published in multiple peer reviewed articles in high-profile journals, such as Science, Plos Genetics and Molecular Biology of Cells. She also serves as a reviewer for many journals.

 Biography
Research Interest :

Her research interest is in multidisciplinary fields including apoptosis, C.elegans genetics, pathogen-host interactions and CRISPR genome editing.

 Research Interest
 Network
Jacqueline Novak

Jacqueline Novak
Walsh University
USA

Biography :

Dr. Jacqueline Novak received her PhD in 1994 from the University of Cincinnati School of Medicine. She did post-doctoral fellowships in the Department of Physiology at the University of Mississippi Medical Center (Jackson, MS) and at Magee Womens Research Institute in Pittsburgh PA. Dr. Novak went on to become an Assistant Professor in the Department of Obstetrics and Gynecology at University of Pittsburgh School of Medicine and Magee Womens Research Institute. In 2005, Dr. Novak moved to Walsh University in North Canton, OH where she is now an associate professor in the Division of Math and Sciences. She is a member of the American Physiological Society.

 Biography
Research Interest :

Relaxin, pregnancy, preeclampsia, hypertension

 Research Interest
 Network
Amar Bahadur Singh

Amar Bahadur Singh
Research Associate
Office of Research & Development,
stanford university
Stanford Affiliated VA Palo Alto Health Care System,
Palo Alto, CA

Biography :

Research Associate: Stanford Affiliated VA Palo Alto Health Care System, Palo Alto, California, (Research advisor: Dr. Jingwen Liu). My current focus research: Characterization of cellular genes that are regulated by diets, natural lipid lowering compounds, and cytokines in liver tissues, primary hepatocytes, and liver cell lines. Promoter analysis to identify critical cis-acting elements and trans-acting factors that play important roles in PPAR gene expression and regulation in liver cells. Regulation of LDLR mRNA levels and PPARs in hepatic lipid metabolism. 2012-2014 Postdoctoral Research: Division of Endocrinology, Gerontology & Metabolism, Stanford University, (Research advisor: Prof. Fredric B. Kraemer). Project was focus on regulation of LDLR mRNA by Berberine. we have generated a Luc-UTR in vivo model to study the regulation of LDLR mRNA stability in liver tissue of living mice, and by using this model we established inverse relationship between hnRNPD abundance and LDLR mRNA levels after BBR treatment of Alb-Luc-UTR mice Amar Bahadur Singh, Ph.D. suggests a critical function of hnRNPD in mediating hepatic LDLR mRNA degradation. We have also identified a novel posttranscriptional regulatory mechanism by which dietary cholesterol inhibits liver LDLR expression via inducing hnRNPD to accelerate LDLR mRNA degradation. 2009-2011 Postdoctoral Research: Molecular Cardiology, Cardiovascular Research Institute, Texas A&M Health Science Center, (Research advisor: Prof. Kenneth M. Baker). Project was focus on molecular mechanisms of RA-mediated signaling in hyperglycemia-induced cardiac remodeling, Using neonatal rat cardiomyocytes, we have demonstrated that hyperglycemia (HG)-induced oxidative stress and activation of the JNK pathway negatively regulated expression/activation of RAR and RXR. The impaired RAR/RXR signaling and oxidative stress/JNK pathway forms a vicious circle, which significantly contributes to hyperglycemia induced cardiomyocyte apoptosis. 2004-2009 Doctoral Research: Biochemistry Division, Central Drug Research Institute, Lucknow, (Research advisor: Dr. Arvind K Srivastava). My doctoral research was to focus on identification of new anti-diabetic and anti-dyslipidemic lead molecules from different source of compounds & exploration of their mechanism of action (s). I was also working on nuclear receptors that are mainly involved in regulation of glucose, cholesterol and lipid metabolism like PPAR, RAR, RXR, LXR and FXR. Simultaneously, I was also screened the new agonists /antagonist ligand molecules from different series of compounds synthesized by medicinal chemistry division of our Institute and are exploring the relevance of these ligands for therapeutics in pathophysiological conditions such as diabetes, dyslipidemia and atherosclerosis. PROFESSIONAL MEMBERSHIP 2010-Present American Heart Association

 Biography
Research Interest :

New drug discovery R&D on diabetes, obesity, hyperlipidemia, and cardiovascular diseases.

 Research Interest
 Network
Jayanthi Repalli

Jayanthi Repalli
Department of Pathology
NYU Langone Medical Center
New York University
USA

Biography :

Jayanthi Repalli is a postdoctoral fellow at the NYU Langone Medical Center. Her research interests lie in the areas of drug design and development by using computational and invivo/invitro techniques. She has identified targets, discovered lead molecules, and optimized them for Alzheimer’s disease and Cancer by using virtual ligand and biochemical screening methodologies. She has graduated from University of South Carolina in 2011 with a doctoral degree in Pharmaceutical Sciences. Her doctoral thesis is entitled “Computational and Pharmacological Approaches to Design Allosteric Thymidylate Synthase Inhibitors.” She also has a Bachelors degree in Pharmacy from G. Pulla Reddy College of Pharmacy in India. Additionally, she is actively involved in consulting projects and provides subject matter expertise to early stage life science investors and entrepreneurs.

 Biography
Research Interest :

Alzheimer’s disease, Aging, Cancer, Cell and molecular biology, Drug design and development, Pharmacology, Stress response, Structural biology

 Research Interest
 Network
Amit Kumar Tyagi

Amit Kumar Tyagi
Department of Experimental Therapeutics,
The University of Texas
Anderson Cancer Center, 
Houston TX,
USA

Biography :

Dr Amit Kumar Tyagi received his PhD degree in Applied Microbiology from Indian Institute of Technology Delhi, New Delhi, India where he studied the antimicrobial potential of different phytochemicals against food spoiling and disease causing microorganisms in in-vivo and in-vitro food models. During his PhD, he was awarded for European grant ‘Erasmus Mundus Corporation Window’ for doing part of his thesis work in University of Bologna, Italy. His work at The university of Texas MD Anderson Cancer Center revealed that TNF exhibit pro-inflammatory activities and may mediate carcinogenesis through the activation of a transcription factor NF-κB. The gene products regulated by NF-κB have now been linked to cellular transformation, tumor cell survival, proliferation, invasion, angiogenesis, metastasis, chemoresistance, and radioresistance. Mostly carcinogens, tumor promoters, growth factors, inflammatory agents, chemotherapeutic agents, radiation, viruses, bacteria, cigarette smoke, alcohol and other life style factors activate NF-κB and another transcription factor STAT3. Dr Tyagi’s research group is working on safe and multi-targeting chemopreventive agents derived from natural resources suppress NF-κB and STAT3 pathway and suppress tumorigenesis.

 Biography
Research Interest :

Study of transcription factors NF-kappaB and STAT3 signaling pathway, death receptor pathway, extrinsic and intrinsic pathway of apoptosis, anticancer properties of natural compounds in both in vitro and nude mouse models, study of cell cycle by flow cytometry, study of oxidative stress in animal models, antioxidants, study of genotoxicity by chromosomal aberration and micronuclei assay, study of gene expression by using western blotting and RT-PCR, DNA binding assay by EMSA, reporter gene expression, Immunohistochemical analysis, studies on both in vivo and in vitro experimental models, SEM, TEM, AFM, Food Microbiology and Food Chemistry, SPME-GCMS.

 Research Interest
 Network
Sahdeo Prasad

Sahdeo Prasad
Cytokine Research Laboratory
Department of Experimental Therapeutics
The University of Texas
Anderson Cancer Center Texas
USA

Biography :

EDUCATION • Ph.D. (Biotechnology), CSJM University, Kanpur, India and Indian Institute of Toxicology Research (CSIR), Lucknow, India, 2010. • MS (Biotechnology), Kumaun University, Nainital, India, 2003. • BS (Biotechnology), Ranchi University, India, 2001. POSTGRADUATE TRAINING • April 2011 - present: Post-Doctoral Fellow, Department of Experimental Therapeutics, The University of Texas, MD Anderson Cancer Center, USA. • November, 2008 – April 2011: Research Intern/Assistant II, Department of Experimental Therapeutics, The University of Texas, MD Anderson Cancer Center, USA. AWARDS/HONORS • National Eligibility Test for lectureship by University Grant commission (CSIR-UGC-NET), New Delhi, Govt. of India, 2003. • Junior Research Fellowship by Indian Council of Medical Research, New Delhi, Govt. of India, 2003 • Graduate Aptitude Test in Engineering (GATE), New Delhi, India MEMBERSHIP OF SCIENTIFIC ORGANIZATIONS • 2005-present: Environmental Mutagenesis Society of India. EDITOR 1. Guest editor in special issue "Curcumin, Inflammation, and Chronic Diseases: How are They Linked?" in journal ‘Molecules’ published by ‘MDPI’. (http://www.mdpi.com/journal/molecules/special_issues/curcumin) 2. Lead guest editor in special issue “Oxidative Stress and Cancer: Advances and Challenges" in journal ‘Oxidative Medicine and Cellular Longevity’ published by ‘Hindawi Publishing Corporation’. (http://www.hindawi.com/journals/omcl/si/548572/cfp/) 3. Editor in SM Group Open Access eBooks entitle “Prevention and Treatment of Cancer by Natural Compounds”. http://www.smgebooks.com/index.php EDITORIAL BOARD MEMBER 1. Indian Journal of Research in Pharmacy and Biotechnology (http://www.ijrpb.com/editorialboard.html) 2. International Journal of Pharmacy and Pharmaceutical Sciences (http://www.ijppsjournal.com/join%20the%20editorial%20board.htm) 3. Advance Techniques in Biology and Medicines (http://esciencecentral.org/journals/editorialboard-advanced-techniques-in-biology-medicine-open-access.php). JOURNAL REVIEWER Cancer Research, Clinical Cancer Research, Molecular Cancer Therapeutics, Cancer Prevention Research, Molecular Cancer Research, Diabetes Technology and Therapeutics, Interdisciplinary Sciences: Computational Life Sciences, BMC Cancer, Biological Sciences, Int J Resp Pulm Med, OMICS-Clinical, Gene Therapy and Molecular Biology, Journal of Ethnopharmacology, Cancer Cell International, Food and Chemical Toxicology, Journal of Nutritional Biochemistry, Journal of Clinical & Experimental Cardiology, Food & Function, Cancer Research & treatment, Arabian Journal of Chemistry, Phytomedicine, Toxicology Reports, Indian Journal of Biochemistry & Biophysics, Current Pharmaceutical Design, PLOS One and many more.

 Biography
Research Interest :

Study of transcription factors NF-kappaB and STAT3 signaling pathway, death receptor pathway, extrinsic and intrinsic pathway of apoptosis, anticancer properties of natural compounds in both in vitro and nude mouse models, study of cell cycle by flow cytometry, study of oxidative stress in animal models, antioxidants, study of genotoxicity by chromosomal aberration and micronuclei assay, study of gene expression by using western blotting and RT-PCR, DNA binding assay by EMSA, reporter gene expression, Immunohistochemical analysis, studies on both in vivo and in vitro experimental models.

 Research Interest
 Network
Yusuf Tutar

Yusuf Tutar
Faculty of Pharmacy
Department of Basic Sciences
Biochemistry Division
Cumhuriyet University
Turkey

Biography :

Dr. Yusuf TUTAR is the Head of Biochemistry Division and the head of Basic Pharmaceutical Sciences Department at Faculty of Pharmacy, Cumhuriyet University, Sivas Turkey. Dr. Tutar is also the Head of Biomedical Engineering Program at the same university. He obtained his M.Sc. and Ph.D. at Oregon State University and Texas Tech University respectively. He pursued his postdoctoral study at National Institutes of Health (NIH/NIDDK), USA. His research focuses on Biochemistry, Biophysics, Genetics and Molecular Biology with specialization in the fields of protein structure-function, protein folding, prion, microrna, pseudogenes, molecular cancer, molecular docking, proteomics, genomics, protein expression and characterization by spectroscopic and calorimetric methods.

 Biography
Research Interest :
 Research Interest
 Network
Martin Ehler

Martin Ehler
German Research Center for Environmental Health
Institute of Biomathematics and Biometry
Germany

Biography :

Martin Ehler came 2008 to the National Institutes of Health after receiving his PhD at the University of Marburg/Germany in mathematics and computer science. As the only mathematician in the Section on Medical Biophysics at NIH, he is committed to interdisciplinary research and has published in mathematical as well as biomedical journals. He uses harmonic analysis together with modern tools in statistics in order to study retinal development and related fields. 

Since 2011, the NIH and the German Science Foundation support his own project on Sparsity and Dimension Reduction in Biomedical Data Analysis at the Helmholtz Zentrum MŸnchen, German Research Center for Environmental Health.






 

 Biography
Research Interest :

Retinal development and related fields.

 Research Interest
 Network
Boris F. Vanyushin

Boris F. Vanyushin
Belozersky Institute of Physical and Chemical Biology
Moscow State University
Russia

Biography :

At Present Belozersky Institute of Physical and Chemical Biology, Moscow State University, Moscow, Russia 1973 1965   D. Sci. (Biochemistry), Moscow State University,1965 1964   Postdoctoral Research Fellow, Virus Research Unit, ARC, Cambridge, England, 1960 1957   Ph.D. (Biochemistry), Moscow State University, 1957 1952   B. S. (Biochemistry), Moscow State University

 Biography
Research Interest :
 Research Interest
 Network
Matthew John Kirkham

Matthew John Kirkham
Department of Cell and Molecular Biology
Karolinska Institute
Stockholm
Sweden

Biography :

In the early stage of my career I participated in several studies that focused on the formation and regulation of the mitotic spindle during the first cell division of the C.elegans embryo, with a specific focus on centriole morphology and the recruitment of pericentriolar material. I then decided that to develop my career and to expand my capacity as an independent researcher to undertake my graduate studies in the controversial subject of the role of caveolae in endocytosis and non-caveolae non-clathrin endocytosis.

I now felt that I would like to apply my skills in my postgraduate studies to a project, which could provide fundamental knowledge of direct relevance to a health problem. I also wanted to expand from mechanisms within the cell to cellular responses within a specific tissue environment. I chose to investigate neurogenesis driven regeneration of dopaminergic neurons in the adult vertebrate Notophthalmus viridescens (the red spotted newt).  This may have direct relevance to the development of future treatments to Parkinson’s disease. I am now investigating how the immune system impinges on the regeneration process.


 

 Biography
Research Interest :

I am a highly motivated independent researcher with experience in cell biology, stem cell biology, and adult neurogenesis

 Research Interest
 Network
Peng Zhang

Peng Zhang
Institute of Genetics and Developmental Biology
Chinese Academy of Sciences
China

Biography :
 Biography
Research Interest :

Nuclear reprogramming and transgenic studies on domestic animals;
Structural and functional genome of ruminants;
Study of gene function based on KO mouse model;
MicroRNA function and evolution.

 Research Interest
 Network
Kyung-Sun Kang

Kyung-Sun Kang
Director
Professor of Adult Stem Cell Research Center
College of Veterinary Medicine
Seoul National University
Korea

Biography :

Kyung-Sun Kang is Professor of College of Veterinary Medicine and founding Director of the Adult Stem Cell Research Center at Seoul National University.

Dr. Kang is a chair of the stem cells steering committee of the Ministry of Education, Science and Technology (MEST) in Korea, and a member of evaluation committee of the governmental performance of Korean Food and Administration (KFDA). He was recently Co-Chair of the German-Korean Workshops for Regenerative Medicine-from basic research to beside. He currently serves a review board directorate for national S&E programs, National Reseqrch Foundation of Korea (NRF). He is a member of the International Society of Stem Cell Research (ISSCR), KSSCR, Korean Society of Toxicology and TERMIS.

Dr. Kang has been working with human adult stem cells for more than 15 years, and his current research focuses on discovering the molecular basis of their pluripotency and differentiation. A key goal of his research is to discover the key elements that control the unique epigenetic mechanisms of human adult stem cell aging and use this knowledge for improved reprogramming methods for human somatic cells and more efficiently expand adult stem cells for clinical usages.

In addition to investigating the fundamental biology of human adult stem cells, Dr. Kang is developing practical applications for these cells for drug discovery, drug delivery, and cell therapy. A major interest of his laboratory is to use stem cells to discover novel therapies for Alzheimer′s disease, Clowns’ disease, Rheumatoid Arthritis and Diabetes.

In addition to his basic and applied research, Dr. Kang is training the next generation of stem cell scientists, domestically and internationally.

 
 

 Biography
Research Interest :

Toxicology, Oncology
Veterinary Public Health, Oncology
Breast Cancer and Stem Cell Biology
 

 Research Interest
 Network
Nailya Akhtyamova

Nailya Akhtyamova
Microbiologist
National University of Uzbekistan
Sweden

Biography :

I was born in Tashkent, Uzbekistan (Central Asia). I have graduated from the National University of Uzbekistan in 1974. I worked as a microbiologist researcher at the Research Institute of Vaccine and Whey, Uzbekistan, Tashkent, Research Institute of Plant Pathology, Uzbekistan, Tashkent and Institute of Genetics and Plant Experimental Biology of Academy of Sciences, Uzbekistan, Tashkent. I received my Ph.D. degree in microbiology from the Scientific Research Institute of Epidemiology, Microbiology and Infectious Diseases of Department of Health, Uzbekistan, 2001. I have been living in Sweden now. I have received Recognition of education and my Ph.D. degree in the Swedish National Agency for Higher Education, Stockholm, 2005.

 Biography
Research Interest :

Pathogen virulence, pathogen antagonist, novel niches of antagonists, intracellular/endofungal bacteria, protoplast fusion, cancer cell.

 Research Interest
 Network

Yavuz Dodurga
Department of Medical Biology
Pamukkale University
School of Medicine
Turkey

Biography :

Dr. Yavuz DODURGA has received his PhD from Ege University Medical Faculty Department of Medical Biology and Genetics. After obtaining his PhD, he is now working in Pamukkale University Medical Faculty Department of Medical Biology and Genetics. I am a good team player, kind and considerate, and always willing to lend a hand. I have been supported with many awards and projects. I have focused on a novel gene which is name “Up Regulated Gene 4” to evaluate correlating with cancer. Satiroglu-Tufan (PhD advisor) and her colleagues, up-regulated expression of a new novel gene have been characterized in the presence of HBV X protein and it is called as “Up-Regulated-Gene-4 (URG4), Up-regulator of Cell Proliferation (URGCP)”. The full-length URG4 clone was 3.607 kb and encodes a polypeptide of 922 amino acids. Analysis of the novel full-length URG4 sequence showed no homology with other previously published genes and localized in the short arm of human chromosome 7 (7p13).  In vitro cell culture experiments revealed that over-expression of URG4, transfected in HepG2 cells, increase the cell proliferation, in the presence or absence of growth factors, increase colony formation in soft agar and to accelerate the tumors formation in mice having suppressed immune system. The results of these experiments are characteristic functions of oncogenes, so it is thought that URG4 is a new potential oncogene, will play important role in multistep hepatocarcinogenesis.

 Biography
Research Interest :

Cell biology, Medical genetics, Molecular biology and genetics, Genetic disorders, Cancer biology, Tumor biology, Cell signaling, Biomarkers, Neuroscience, miRNA

 Research Interest
 Network
Surajit Sarkar

Surajit Sarkar
Department of Genetics
University of Delhi
India
Read Interview session with Surajit Sarkar

Biography :

Dr. Surajit Sarkar received his Ph.D in Zoology (Developmental Genetics) in 2007 from Banaras Hindu University, Varanasi, India, where he studied the role(s) of Hsp60during various stages of development and fertility in Drosophila melanogaster. Subsequently, he joined Department of Genetics, University of Delhi (South Campus), New Delhi, as Assistant Professor and still working there.He worked as Visiting Associate at California Institute of Technology, Pasadena, USA, during 2010-11.

 Biography
Research Interest :

Dr. Sarkar’s group is mostly focused on harnessing the power of Drosophila genetics to address some basic questions associated with developmental genetics and for exploring the cellular and developmental basis of some fatal human neurodegenerative disorders and aging phenomenon.

 Research Interest
 Network
Manchikatla Venkat Rajam

Manchikatla Venkat Rajam
Department of Genetics
University of Delhi
India
Read Interview session with Manchikatla Venkat Rajam

Biography :

Dr. M. V.  Rajam is Professor of Genetics at the University of Delhi South Campus, New Delhi and has over three decades of research experience in the fields of plant biotechnology and polyamine physiology, and recently RNAi applications in plants, and published over 110 papers, including book chapters/reviews.  Dr. Rajam received his M. Sc (1979) and Ph. D (1983) degrees from Kakatiya University, Warangal, AP, India and had a postdoctoral research experience at Yale University, New Heaven, and Boyce Thompson Institute, Cornell University, Ithaca, USA (1984-85). He is a Fellow of The National Academy of Sciences, India and Fellow of The Indian Academy of Agricultural Sciences, and member of several learned scientific societies.  He serves as a member of editorial board and Associate Editor of some important international journals, and a reviewer for many international and national journals.  He has also received several honors and awards.

 Biography
Research Interest :

My research uses transgenic and other molecular approaches like RNAi to address a wide range of questions in plant development and stress responses. The current major research interests of my laboratory is to use RNAi technology to unravel the functions of polyamine biosynthesis genes in various developmental processes, including fruit ripening, stress responses, and to develop transgenic crops for disease, insect and nematode resistance through plant RNAi-mediated silencing of vital genes of the target pathogens and pests.
 

 Research Interest
 Network

Parmit Kumar Singh
National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH)
USA

Biography :

I completed my PhD at Centre for Cellular and Molecular Biology (CCMB), Hyderabad, India. I determined the threshold size of duplicated DNA that titrates repeat induced point mutation (RIP) machinery. Moreover, I identified the first wild-isolate strain of Neurospora as a dominant suppressor of meiotic silencing. Both RIP and meiotic silencing are genome defense process in Neurospora. Currently, I am trying to understand the integration preference of HIV-1 and my results, based on one million integration sites of HIV-1 in human cultured cells, showed that HIV-1 has preference for the highly spliced and cancer genes. I am also involved in teaching at the Foundation for Advanced Education in the Science (FAES), and Uniformed Services University of the Health Sciences (USUHS), Bethesda, Maryland, USA.

 Biography
Research Interest :
 Research Interest
 Network

Sandeep Kumar Kar
Assistant Professor
Super specialty department of Cardiac Anesthesiology
Institute of Postgraduate Medical Education & Research
Kolkata
India

Biography :

Dr. Sandeep Kumar Kar is presently working as Assistant Professor, Super specialty department of Cardiac Anesthesiology, Institute of Postgraduate Medical Education & Research, and Kolkata, India. He has represented India in several world congress in Anesthesiology and Critical Care. He has published more than fifty research articles and reviews in high impact international journals including Anesthesiology (Journal of American Society of Anesthesiology). He is in the Editorial board of several journals and Editor of Translational Biomedicine, Insight of Blood Pressure, Journal of Neurosurgery, and Interventional Cardiology. He has won several international and National awards like Janak Mehta National Award for best paper in Cardiac Anesthesiology, B Braun Scholar of the year (2012), ESOP Scholarship (NWAC 2013) and presented papers and lectures in several National and International conferences. He is also a Poet and Writer of international repute with poetry published in several international Journals.

 Biography
Research Interest :
 Research Interest
 Network
 
 
 
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