alexa Pulmonary Arterial Hypertension from Hepatic HHT | Open Access Journals
ISSN: 2165-8048
Internal Medicine: Open Access
Make the best use of Scientific Research and information from our 700+ peer reviewed, Open Access Journals that operates with the help of 50,000+ Editorial Board Members and esteemed reviewers and 1000+ Scientific associations in Medical, Clinical, Pharmaceutical, Engineering, Technology and Management Fields.
Meet Inspiring Speakers and Experts at our 3000+ Global Conferenceseries Events with over 600+ Conferences, 1200+ Symposiums and 1200+ Workshops on
Medical, Pharma, Engineering, Science, Technology and Business

Pulmonary Arterial Hypertension from Hepatic HHT

Yutian Sun1, Jinyi Wu2 and Xiaowei Li2*
1Pharmaceutical Department, China-Japan Union Hospital, Jilin University, Changchun 130033, PR China
2Cardiovacular Department, China-Japan Union Hospital, Jilin University, Changchun 130033, PR China
Corresponding Author : Xiaowei Li
Cardiovascular Department
China-Japan Union Hospital
Jilin University, Changchun 130033
PR China
Received: September 01, 2015 Accepted: September 20, 2015 Published: September 27, 2015
Citation: Sun Y, Wu J, Li X (2015) Pulmonary Arterial Hypertension from Hepatic HHT. InternMed 5:109. doi:10.4172/2165-8048.1000i109
Copyright: © 2015 Sun Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Related article at Pubmed, Scholar Google

Visit for more related articles at Internal Medicine: Open Access

Clinical Image
A 42-year female was admitted to our hospital complaining of repeated cough and pant for 2 years. The patient had intermittent nasal bleeding, and her family (including her mother, her aunt) had also similar medical history. Many capillary blood vessels were dilated in her finger and tongue (Figures 1 and 2).
No heart murmur or rhonchi was audible on the chest auscultation. Hepatosplenomegaly was not noted on abdominal field palpation. Echocardiography suggested right atrium enlargement, right ventricle enlargement, and pulmonary arterial hypertension. Abdominal ultrasound suspected hepatic hemangioma.
Chest radiography showed mild cardiomegaly with increasing pulmonary vascular markings (Figure 3). Contrast-enhanced CT of chest revealed the same cardiac alterations as echocardiography (Figure 4). Hepatic contrast-enhanced CT revealed parenchymal perfusion disorders, arteriosystemic shunts and arterioportal shunts (Figures 5 and 6).
Hereditary Hemorrhagic Telangiectasia (HHT) is mucocutaneous or visceral angiodysplastic lesions, which may be distributed throughout cardiovascular system. Currently, the pathogeneses of the disease could result from genetic mutations that interfere with angiogenesis and its control mechanisms [1].
Hepatic involvement occurs in 30% to 73% of patients with HHT; most of them are symptomatic or have a slight elevation of r-GGT [2]. Hepatic vascular lesions range from tiny telangiectases to transient perfusion abnormalities and large confluent focal vascular masses.
Three different and often concurrent types of intrahepatic shunts are responsible for the parenchymal, vascular and bile duct signs. An arteriovenous shunt can, on rare occasions, be responsible for highoutput heart failure as described in our case.

Figures at a glance


Figure Figure Figure
Figure 1 Figure 2 Figure 3
Figure Figure Figure
Figure 4 Figure 5 Figure 6
Select your language of interest to view the total content in your interested language
Post your comment

Share This Article

Relevant Topics

Recommended Conferences

Article Usage

  • Total views: 11490
  • [From(publication date):
    October-2015 - Jul 22, 2017]
  • Breakdown by view type
  • HTML page views : 7738
  • PDF downloads :3752

Post your comment

captcha   Reload  Can't read the image? click here to refresh

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

1-702-714-7001Extn: 9037

Business & Management Journals


1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version